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Chemistry, metabolism, and biological functions of sialic acids.
  • R. Schauer
  • Chemistry, Medicine
  • Advances in carbohydrate chemistry and…
  • 1982
Publisher Summary This chapter discusses the chemistry, metabolism, and biological functions of sialic acids. Interest in the sialic acids has rapidly increased in recent years, especially because ofExpand
  • 947
  • 30
Sialic acids as regulators of molecular and cellular interactions
  • R. Schauer
  • Biology, Medicine
  • Current Opinion in Structural Biology
  • 19 August 2009
The wide occurrence of sialic acids (Sia) in various chemical forms linked as monomers or polymers in an outstanding position in a multitude of complex carbohydrates of animals and microorganismsExpand
  • 482
  • 20
  • PDF
Achievements and challenges of sialic acid research
  • R. Schauer
  • Biology, Medicine
  • Glycoconjugate Journal
  • 1 July 2000
Sialic acids are one of the most important molecules of life, since they occupy the terminal position on macromolecules and cell membranes and are involved in many biological and pathologicalExpand
  • 537
  • 16
Sialic acids: fascinating sugars in higher animals and man.
Sialic acids are acidic monosaccharides, which are among the most important molecules of higher animals, and occur in some microorganisms. They are bound to complex carbohydrates and occupy prominentExpand
  • 358
  • 15
Sialic Acids in Molecular and Cellular Interactions
Sialic acids (Sias) are terminal components of many glycoproteins and glycolipids especially of higher animals. In this exposed position they contribute significantly to the structural propertiesExpand
  • 435
  • 14
The sialidase superfamily and its spread by horizontal gene transfer
Sialidases (neuraminidases, EC belong to a class of glycosyl hydrolases that release terminal N‐acylneuraminate (slalic acid) residues from glycoproteins, glycolipids, and polysaccharides.Expand
  • 163
  • 14
Structure, function and metabolism of sialic acids
Abstract. Sialic acids represent a family of sugar molecules with an unusual and highly variable chemical structure that are found mostly in the terminal position of oligosaccharide chains on theExpand
  • 347
  • 10
New chromatographic system for the rapid analysis and preparation of colostrum sialyloligosaccharides.
A new thin-layer chromatographic system on silica gel for the separation of sialyloligosaccharides is described. Calibration of the system with standard milk and colostrum sialyloligosaccharides isExpand
  • 133
  • 7
Transmissible gastroenteritis coronavirus, but not the related porcine respiratory coronavirus, has a sialic acid (N-glycolylneuraminic acid) binding activity.
The hemagglutinating activity of transmissible gastroenteritis virus (TGEV), an enteric porcine coronavirus, was analyzed and found to be dependent on the presence of alpha-2,3-linked sialic acid onExpand
  • 115
  • 7
Distribution of developmentally regulated trans-sialidases in the Kinetoplastida and characterization of a shed trans-sialidase activity from procyclic Trypanosoma congolense.
The expression of developmentally regulated sialidase and trans-sialidase activities in kinetoplastid protozoa was investigated. The occurrence of these enzymes was found not to be a common featureExpand
  • 58
  • 7