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Measurement of androgen receptor in cytosols from normal, benign hypertrophic and cancerous human prostates.
TLDR
The binding of R 1881 in cytosols from the normal, benign hypertrophic and cancerous human prostates was examined, and the binding in the presence of triamcinolone acetonide exhibited the characteristics of androgen receptor. Expand
Binding of mibolerone to androgen receptor of benign hypertrophic human prostate. Comparison with R1881.
TLDR
Mibolerone seems to be a suitable ligand for measuring the androgen receptor, but when compared with R 1881 no special merits in using miboler one were detected. Expand
Binding of dihydrotestosterone, R 1881 and R 5020 in cytosols from normal, benign hypertrophic and cancerous human prostates.
TLDR
The binding of dihydrotestosterone, R 1881 and R 5020 was examined in cytosols of normal, benign hypertrophic and cancerous tissues of the human prostates and maximum binding sites seemed to be greater in normal tissues than in the pathological ones. Expand
Progestin-binding protein in human benign prostatic hypertrophy.
TLDR
Although nuclear extract by 0.4 M KCl showed R 1881 binding, the extract did not contain the R 5020-binding protein, and this suggested that the progestin-bindingprotein observed in the cytosols does not seem to be the steroid receptor. Expand
Androphilic proteins in the human prostate
TLDR
Maximum binding sites to dihydrotestosterone, R1881, and R5020 in cytosols were very similar among “normal” and pathological prostates except that dihy‐drotestosterone binding was higher in “ normal” prostates than in the pathological ones. Expand
Changes in cytosolic androgen receptor after administration of testosterone of androgen-dependent mouse mammary tumor (Shionogi carcinoma) and its sublines of altered androgen dependency.
TLDR
It was concluded that the depletion and replenishment of the androgen receptor in cytosols of the tumors were caused by receptor recycling, similar to that observed in the less androgen-dependent tumors. Expand
Properties of progestin-binding protein in benign hypertrophic human prostate.
TLDR
The results obtained in the present study suggest that the progestin-binding component in the benign prostatic hypertrophy is not the progesterone receptor but a high affinity binder for progestins whose physiological role is not clear at present. Expand
Prognostic significance of third-line treatment for patients with metastatic castration-resistant prostate cancer: comparative assessments between cabazitaxel and other agents
TLDR
The introduction of cabazitaxel as a third-line agent could markedly improve the prognostic outcomes of mCRPC patients. Expand
Molecular Mechanism Mediating Cytotoxic Activity of Cabazitaxel in Docetaxel-resistant Human Prostate Cancer Cells
Background/Aim: Cabazitaxel is known to be effective in patients with castration-resistant prostate cancer (CRPC) showing resistance to docetaxel. The objective of this study was to investigate theExpand
Perioperative outcomes in patients undergoing robot‐assisted partial nephrectomy: Comparative assessments between complex and non‐complex renal tumors
The aim of this study was to investigate the effects of renal tumor complexity on perioperative outcomes in patients receiving robot‐assisted partial nephrectomy (RAPN).