• Publications
  • Influence
How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions.
TLDR
This review considers recent findings regarding GC action and generates criteria for determining whether a particular GC action permits, stimulates, or suppresses an ongoing stress-response or, as an additional category, is preparative for a subsequent stressor.
The Influence of Social Hierarchy on Primate Health
TLDR
Whether it is high- or low-ranking animals that are most stressed in a dominance hierarchy turns out to vary as a function of the social organization in different species and populations are considered.
Why Zebras Don't Get Ulcers
TLDR
Why Zebras Don't Get Ulcers explains how prolonged stress causes or intensifies a range of physical and mental afflictions, including depression, ulcers, colitis, heart disease, and more, and provides essential guidance to controlling the authors' stress responses.
Reproduction and Resistance to Stress: When and How
TLDR
Four mechanisms underlying resistance of the gonadal axis to stress are suggested, likely genetically determined, and their expression may depend upon a complex interaction with environmental factors.
Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders.
  • R. Sapolsky
  • Psychology, Biology
    Archives of general psychiatry
  • 1 October 2000
TLDR
This review examines the evidence for hippocampal atrophy in Cushing syndrome, which is characterized by a pathologic oversecretion of glucocorticoids; (2) episodes of repeated and severe major depression; (3) posttraumatic stress disorder and what cellular mechanisms underlie the overall decreases in hippocampal volume.
The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.
TLDR
The goal in the study of aging is not to halt the process, because the authors can no more be cured of aging than of birth, but to slow and soften the sharpest edges of the biological unraveling that constitutes aging.
Social Status and Health in Humans and Other Animals
TLDR
It is argued that socioeconomic status (SES) is the nearest human approximation to social rank and that SES dramatically influences health, as well as the varieties of hierarchical systems in animals.
Stress and cognitive function
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