• Publications
  • Influence
Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial.
TLDR
Among patients with a history of colorectal adenomas, the use of rofecoxib was associated with an increased cardiovascular risk, and cardiovascular mortality was similar in the two groups.
Burden of gastrointestinal disease in the United States: 2012 update.
TLDR
The burden of GI disease in the United States is estimated and the most common GI symptom is abdominal pain, while the total cost for outpatient GI endoscopy examinations was $32.4 billion.
A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer.
TLDR
Daily use of aspirin is associated with a significant reduction in the incidence of colorectal adenomas in patients with previous coloreCTal cancer.
The burden of selected digestive diseases in the United States.
TLDR
The most prevalent diseases were non-food-borne gastroenteritis, food-borne illness, gastroesophageal reflux disease, and irritable bowel syndrome, followed by gallbladder disease, which had the highest annual direct costs in the United States.
Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults.
TLDR
This study demonstrates a substantial economic burden of IBD and can be used to inform health policy as well as identify sociodemographic factors influencing these costs.
A randomized trial of aspirin to prevent colorectal adenomas.
TLDR
Low-dose aspirin has a moderate chemopreventive effect on adenomas in the large bowel, using generalized linear models to compute risk ratios and 95 percent confidence intervals.
Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.
TLDR
Folic acid at 1 mg/d does not reduce colorectal adenoma risk and is associated with higher risks of having 3 or more adenomas and of noncolorectAL cancers.
Burden of Gastrointestinal, Liver, and Pancreatic Diseases in the United States.
TLDR
The most recent data were obtained from the Centers for Disease Control and Prevention, the Agency for Healthcare Research and Quality, and the National Cancer Institute to estimate the burden and cost of GI and liver disease in the United States.
Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group.
TLDR
Calcium supplementation is associated with a significant - though moderate - reduction in the risk of recurrent colorectal adenomas, independent of initial dietary fat and calcium intake.
Is there publication bias in the reporting of cancer risk in Barrett's esophagus?
TLDR
There was a strong correlation between cancer risk and the size of the study, with small studies reporting much higher risks of cancer than larger studies, and publication bias may be overestimated in the literature due to publication bias.
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