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Testosterone and sex hormone-binding globulin predict the metabolic syndrome and diabetes in middle-aged men.
OBJECTIVE In men, hypoandrogenism is associated with features of the metabolic syndrome, but the role of sex hormones in the pathogenesis of the metabolic syndrome and diabetes is not well… Expand
Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction.
- T. Lakka, J. Venäläinen, R. Rauramaa, R. Salonen, J. Tuomilehto, J. Salonen
- The New England journal of medicine
- 2 June 1994
BACKGROUND Previous studies have suggested that higher levels of regular physical activity and cardiorespiratory fitness are associated with a reduced risk of coronary heart disease. We investigated… Expand
Autoantibody against oxidised LDL and progression of carotid atherosclerosis
Oxidative modification of LDL renders it immunogenic and autoantibodies to epitopes of oxidised LDL, such as malondialdehyde (MDA)-lysine, are found in serum and recognise material in atheromatous… Expand
MKS1, encoding a component of the flagellar apparatus basal body proteome, is mutated in Meckel syndrome
Meckel syndrome (MKS) is a severe fetal developmental disorder reported in most populations. The clinical hallmarks are occipital meningoencephalocele, cystic kidney dysplasia, fibrotic changes of… Expand
Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men.
BACKGROUND Physical activity has been advocated as an important factor in the primary prevention of non-insulin-dependent diabetes mellitus (NIDDM), but information concerning the specific… Expand
Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men.
BACKGROUND Even though previous studies have suggested an association between high fish intake and reduced coronary heart disease (CHD) mortality, men in Eastern Finland, who have a high fish intake,… Expand
C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men
Aims/hypothesisLow-grade inflammation has been implicated in the development of Type 2 diabetes and cardiovascular disease, but its role in the pathogenesis of the metabolic syndrome is unclear. We… Expand
The Meckel syndrome: clinicopathological findings in 67 patients.
- R. Salonen
- Biology, Medicine
- American journal of medical genetics
- 1 August 1984
A nationwide study on the Meckel syndrome (MS) was carried out covering retrospectively the years 1970-1979 and prospectively the years 1980-1981. Sixty-seven cases from 48 Finnish families were… Expand
Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) study: a randomized trial of the effect of vitamins E and C on 3‐year progression of carotid atherosclerosis
Abstract. Salonen JT, Nyyssönen K, Salonen R, Lakka H‐M, Kaikkonen J, Porkkala‐Sarataho E, Voutilainen S, Lakka TA, Rissanen T, Leskinen L, tuomainen T‐P, Valkonen V‐P, Ristonmaa U (University of… Expand
Sex hormones, inflammation and the metabolic syndrome: a population-based study.
- D. Laaksonen, L. Niskanen, +5 authors J. Salonen
- Biology, Medicine
- European journal of endocrinology
- 1 December 2003
OBJECTIVE Mild hypoandrogenism in men is associated with features of the metabolic syndrome, but the association with the metabolic syndrome itself using an accepted definition has not been… Expand