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An evaluation of the implementation of the Cramer classification scheme in the Toxtree software
Risk assessment for most human health effects is based on the threshold of a toxicological effect, usually derived from animal experiments. The Threshold of Toxicological Concern (TTC) is a conceptExpand
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Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients.
Based on chemical, cellular, and molecular understanding of dermal sensitization, an exposure-based quantitative risk assessment (QRA) can be conducted to determine safe use levels of fragranceExpand
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The Dermal Sensitisation Threshold- a TTC approach for allergic contact dermatitis.
  • R. Safford
  • Medicine
  • Regulatory toxicology and pharmacology : RTP
  • 1 July 2008
The Threshold of Toxicological Concern (TTC) is a useful concept that is becoming of increasing interest as an addition to the arsenal of tools used for characterising the toxicological risk of humanExpand
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Barn Owl Tyto alba
The Barn Owl has nearly world-wide distribution,bei ng absent from only the high Latitudes. It has been introduced int o some Pacific islands for rat control and is provided nest boxes in MalaysianExpand
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Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains.
An essential step in ensuring the toxicological safety of ingredients in consumer products is the evaluation of their skin sensitising potential. Where skin exposure is low, it is possible to conductExpand
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Strategies for Land‐Bird Conservation on Mauritius
The native wildlife of Mauritius is highly threatened by a variety of influences other than habitat destruction. Protection from habitat destruction alone cannot guarantee its conservation and theExpand
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Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive.
The evaluation of chemicals for their skin sensitising potential is an essential step in ensuring the safety of ingredients in consumer products. Similar to the Threshold of Toxicological Concern,Expand
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A new species of nightjar from Ethiopia
A new species of nightjar is described from a single wing salvaged from a road corpse in 1992 on the Nechisar Plains, Ethiopia. The species is unknown in life. The wing is highly distinctive,Expand
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Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied.
An essential step in ensuring the toxicological safety of chemicals used in consumer products is the evaluation of their skin sensitising potential. The sensitising potency, coupled with informationExpand
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