• Publications
  • Influence
Magnesium Deficiency: A Cause of Heterogenous Disease in Humans
  • R. Rude
  • Medicine
  • Journal of bone and mineral research : the…
  • 1 April 1998
TLDR
Mg is actively transported into and out of cells and is influenced by various hormonal and pharmacological factors which perhaps regulate the intracellular Mg concentration and hence activity of Mg-sensitive enzymes. Expand
Disorders of magnesium metabolism.
  • J. Nadler, R. Rude
  • Medicine
  • Endocrinology and metabolism clinics of North…
  • 1 September 1995
TLDR
Physicians should maintain a high index of suspicion for magnesium depletion in patients at high risk and should implement therapy early. Expand
Sexual dimorphism in plasma leptin concentration.
TLDR
Postmenopausal women had still higher leptin levels than men of similar age, and their levels were not different from those in younger women, which suggests that women may be resistant to its putative lipostatic actions and that it may have a reproductive function. Expand
Skeletal and Hormonal Effects of Magnesium Deficiency
TLDR
The notion at dietary Mg intake at levels not uncommon in humans may perturb bone and mineral metabolism and be a risk factor for osteoporosis is supported. Expand
Magnesium deficiency produces insulin resistance and increased thromboxane synthesis.
TLDR
Dietary-induced magnesium deficiency increases thromboxane urinary concentration and enhances angiotensin-induced aldosterone synthesis, which are associated with a decrease in insulin action, suggesting that magnesium deficiency may be a common factor associated with insulin resistance and vascular disease. Expand
Magnesium metabolism and deficiency.
  • R. Rude
  • Medicine
  • Endocrinology and metabolism clinics of North…
  • 1 June 1993
TLDR
Clinically, magnesium deficiency may present with neuromuscular hyperexcitability, hypocalcemia, hypokalemia, and cardiac arrhythmias, and magnesium therapy appears to improve survival in patients with myocardial infarction. Expand
FUNCTIONAL HYPOPARATHYROIDISM AND PARATHYROID HORMONE END‐ORGAN RESISTANCE IN HUMAN MAGNESIUM DEFICIENCY
TLDR
Evidence is provided for impaired parathyroid gland function in most of the magnesium deficient patients with hypocalcaemia, and the rapidity with which serum IPTH rose in response to magnesium therapy indicates that this may reflect a defect inParathyroid hormone (PTH) secretion rather than its biosynthesis. Expand
Magnesium Deficiency in Critical Illness
  • G. Tong, R. Rude
  • Medicine
  • Journal of intensive care medicine
  • 1 January 2005
TLDR
Magnesium therapy is not supported in the treatment of acute myocardial infarction and is presently undergoing evaluation for thetreatment of severe asthma exacerbation, for the prevention of postcoronary bypass grafting dysrhythmias, and as a neuroprotective agent in acute cerebral ischemia. Expand
Comparative study of alendronate versus etidronate for the treatment of Paget's disease of bone.
TLDR
Alendronate appears to be a highly effective treatment for Paget's disease of bone that offers an important therapeutic advance over etidronate and had a safety profile similar to that of etidronsate. Expand
Intracellular Free Magnesium Deficiency Plays a Key Role in Increased Platelet Reactivity in Type II Diabetes Mellitus
TLDR
It is suggested that type II diabetic patients have intracellular Mg2+ deficiency and that Mg deficiency may be a key factor in leading to enhanced platelet reactivity in type II diabetes, and Mg supplementation may provide a new therapeutic approach to reducing vascular disease in patients with diabetes. Expand
...
1
2
3
4
5
...