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Proteolytic cleavage of the viral glycoproteins and its significance for the virulence of Newcastle disease virus.
On the origin of the human influenza virus subtypes H2N2 and H3N2.
Natural and experimental Borna disease in animals.
Borna disease (BD) is a transmissible, progressive polioencephalomyelitis of horses and sheep, which are the main natural hosts. It occurs sporadically in endemic areas of Germany and Switzerland,…
Behavioral disease in rats caused by immunopathological responses to persistent borna virus in the brain.
Borna virus replicated persistently in the brains of rats, causing frenzied and apathetic behavioral states in sequence but no mortality. The transient frenzied behavior was caused by an…
Activation of influenza A viruses by trypsin treatment.
Pathogenesis of Borna disease in rats: immune-mediated viral ophthalmoencephalopathy causing blindness and behavioral abnormalities.
- O. Narayan, S. Herzog, K. Frese, H. Scheefers, R. Rott
- Medicine, BiologyThe Journal of infectious diseases
- 1 August 1983
The frenzied behavior and subsequent blindness in immunocompetent adults were attributed to a uniquely transient immunopathologic reaction targeted to centers in the limbic system and retinal neurons.
Interactions between bacteria and influenza A virus in the development of influenza pneumonia.
- H. Scheiblauer, M. Reinacher, M. Tashiro, R. Rott
- Biology, MedicineThe Journal of infectious diseases
- 1 October 1992
Plasminogen-activating streptococci and staphylococci facilitate viral replication and pathogenicity of plasmin-sensitive influenza virus strains by amplification of the plAsminogen/plasmin system.
Axonal transport of Borna disease virus along olfactory pathways in spontaneously and experimentally infected rats
- J. A. Morales, S. Herzog, C. Kompter, K. Frese, R. Rott
- Biology, MedicineMedical Microbiology and Immunology
Detailed immunohistological studies showed clearly that after experimental i.n. infection, the infecting virus migrates intraaxonally from the neuroreceptors in the olfactory epithelium into the brain, and it is suggested that i.N. transmission is an important route of natural BDV infection.
Role of Staphylococcus protease in the development of influenza pneumonia
Data are presented which show that some S. aureus strains secrete a protease which exerts a decisive influence on the outcome of influenza virus infection in mice by cleavage activation of the virus haemag-glutinin.
Purification and properties of an intranuclear virus-specific antigen from tissue infected with Borna disease virus.
A virus-specific antigen was extracted from brains of rats and from MDCK cells infected with Borna disease (BD) virus and purified to homogeneity by immunoaffinity chromatography and HPLC and showed the intranuclear fluorescence typical for BD virus-infected cells.