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Study of the anti-hyperglycemic effect of plants used as antidiabetics.
TLDR
The results showed that eight out of the 28 studied plants significantly decrease the hyperglycemic peak and/or the area under the glucose tolerance curve, suggesting the validity of their clinical use in diabetes mellitus control, after their toxicological investigation.
Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial.
TLDR
In conclusion, the HsHMP exerted important antihypertensive effectiveness with a wide margin of tolerability and safety, while it also significantly reduced plasma ACE activity and demonstrated a tendency to reduce serum sodium concentrations without modifying potassium levels.
Effect of zinc replacement on lipids and lipoproteins in type 2-diabetic patients.
TLDR
The assessment of lipid profile from type 2-diabetes mellitus patients treated with hypoglycemic therapy drugs, who additionally presented zinc levels lower than average in Mexican reference, suggests zinc sulfate supplementation may be a therapeutical resource to recover some functioning and improve life span.
Effect of static and dynamic exercise on heart rate and blood pressure variabilities.
TLDR
Instead of the vagal withdrawal and sympathetic augmentation observed during dynamic exercise, the increase in the overall HRV and the MF component during static exercise suggest an increased activity of both autonomic branches.
Investigation on the hypoglycaemic effects of extracts of four Mexican medicinal plants in normal and Alloxan‐diabetic mice
TLDR
Three of the WEE studied conserved the hypoglycaemic activity originally detected in the traditional preparations of the studied antidiabetic plants, and it appears that these extracts require the presence of insulin to show hypoglycasemic activity.
Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice.
TLDR
Aloe vera gel could be effective for the control of insulin resistance and protect animals against unfavorable results on HOMA-IR, which was observed in the negative control group.
Monosodium glutamate neonatal intoxication associated with obesity in adult stage is characterized by chronic inflammation and increased mRNA expression of peroxisome proliferator-activated receptors
TLDR
The MSG neonatal neuro-intoxication in mice may provide a model of obesity and inflammation characterized by the dual activation of PPARα and PPARγ, which might offer new insights into the mechanism of inflammatory diabetes in obesity leading to steatohepatitis, as well as a suitable model to study the role of new therapeutic agents to prevent or reduce insulin resistance, the inflammatory state and liver steatosis.
Experimental study of the hypoglycemic effect of some antidiabetic plants.
TLDR
The results showed that tolbutamide and studied plants (except Aloe barbadensis) decreased significantly the area under glucose tolerance curve, in relation with the water control.
Evaluation of the hypoglycemic effect of Cucurbita ficifolia Bouché (Cucurbitaceae) in different experimental models.
TLDR
The juice administered by intraperitoneal route showed an acute hypoglycemic effect in alloxan-diabetic mice and daily oral administration of this preparation showed a highly significant reduction of the glycemia after 14 days of treatment.
Effect of Hibiscus sabdariffa on obesity in MSG mice.
TLDR
The data confirm the anti-obesity effect of Hibiscus sabdariffa reported by the Mexican population and reduce body weight gain in obese mice and increased liquid intake in healthy and obese mice.
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