Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium
- L. Balsam, A. Wagers, J. Christensen, T. Kofidis, I. Weissman, R. Robbins
- Biology, Medicine
- Nature
- 8 April 2004
Under conditions of tissue injury, myocardial replication and regeneration have been reported. A growing number of investigators have implicated adult bone marrow (BM) in this process, suggesting… Expand
Human tissue-engineered blood vessels for adult arterial revascularization
- N. L'heureux, N. Dusserre, +9 authors T. N. McAllister
- Medicine
- Nature Medicine
- 4 October 2007
There is a crucial need for alternatives to native vein or artery for vascular surgery. The clinical efficacy of synthetic, allogeneic or xenogeneic vessels has been limited by thrombosis, rejection,… Expand
Drug Screening Using a Library of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes Reveals Disease-Specific Patterns of Cardiotoxicity
Background— Cardiotoxicity is a leading cause for drug attrition during pharmaceutical development and has resulted in numerous preventable patient deaths. Incidents of adverse cardiac drug reactions… Expand
A nonviral minicircle vector for deriving human iPS cells
- Fangjun Jia, K. Wilson, +9 authors J. Wu
- Biology, Medicine
- Nature Methods
- 1 March 2010
Owing to the risk of insertional mutagenesis, viral transduction has been increasingly replaced by nonviral methods to generate induced pluripotent stem cells (iPSCs). We report the use of… Expand
Novel Index for Invasively Assessing the Coronary Microcirculation
Background—A relatively simple, invasive method for quantitatively assessing the status of the coronary microcirculation independent of the epicardial artery is lacking. Methods and Results—By using… Expand
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells.
Familial hypertrophic cardiomyopathy (HCM) is a prevalent hereditary cardiac disorder linked to arrhythmia and sudden cardiac death. While the causes of HCM have been identified as genetic mutations… Expand
Immunogenicity and Immunomodulatory Properties of Umbilical Cord Lining Mesenchymal Stem Cells
- T. Deuse, M. Stubbendorff, +8 authors S. Schrepfer
- Biology, Medicine
- Cell transplantation
- 1 June 2011
We here present an immunologic head-to-head comparison between human umbilical cord lining mesenchymal stem cells (clMSCs) and adult bone marrow MSCs (bmMSCs) from patients >65 years of age. clMSCs… Expand
Transcriptional and Functional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes
- F. Cao, Roger A. Wagner, +9 authors J. Wu
- Biology, Medicine
- PloS one
- 22 October 2008
Human embryonic stem cells (hESCs) can serve as a potentially limitless source of cells that may enable regeneration of diseased tissue and organs. Here we investigate the use of human embryonic stem… Expand
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells
- N. Sun, N. Panetta, +8 authors J. Wu
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 15 September 2009
Ectopic expression of transcription factors can reprogram somatic cells to a pluripotent state. However, most of the studies used skin fibroblasts as the starting population for reprogramming, which… Expand
Risk factors for the development of obliterative bronchiolitis after lung transplantation.
- R. Girgis, I. Tu, +9 authors J. Theodore
- Medicine
- The Journal of heart and lung transplantation…
- 1 December 1996
BACKGROUND
Acute rejection has emerged as an important risk factor for obliterative bronchiolitis after lung transplantation. We performed a multivariate analysis to assess the impact of additional… Expand