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Schisantherin A Exhibits Anti-inflammatory Properties by Down-Regulating NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Treated RAW 264.7 Cells
It is found that schisantherin A may inhibit LPS-induced production of inflammatory cytokines by blocking NF-κB and MAPKs signaling in RAW264.7 cells.
New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera and Their Proinflammatory Cytokine Inhibitory Activities
Investigation of the fruits of Schisandra sphenanthera led to the isolation of two new dibenzocyclooctadiene lignans, methylgomisin O (1) and chloromethyl schisantherin B (2), together with twelve…
Schisanlactone G, a new 3,4-seco-lanostane triterpenoid from Schisandra sphenanthera
Polyanthumin, a novel cyclobutane chalcone trimmer from Memecylon polyanthum
- G. Chen, C. Cui, A. Qi, Chang‐Wei Li, Zun-Wei Tao, R. Ren
- ChemistryJournal of Asian natural products research
- 26 January 2015
A novel unusual trimmer chalcone, polyanthumin, together with five known compounds myricetin 3-O-(3″-O-galloyl)-α-l-rhamnopyranoside, which provided the first example of these class flavonoids from the family Melastomataceae and the antitumor activities for 2–4 were reported for the first time in this study.
Isolation of two new prenylflavonols from Epimedium brevicornum and their effects on cytokine production in vitro.
Results suggested that compound 1 may have anti-inflammatory activity in lipopolysaccharide (LPS)-stimulated mouse macrophages, and the biogenetic relationships among compounds 1 and 2 are discussed.
New Dibenzocyclooctadiene Lignans from Schisandra sphenanthera and Their Pro-inflammatory Cytokine Inhibitory Activities