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Flowering Plants of Jamaica
The exploration and knowledge of the flora and vegetation of the West Indies ran far ahead of that of many countries much closer to the great historical centers of systematic botany mainly becauseExpand
Phosphylated tyrosine in albumin as a biomarker of exposure to organophosphorus nerve agents
The tyrosine adducts with soman and tabun were detected in guinea pigs receiving therapy 7 days following subcutaneous administration of five times the LD50 dose of the respective nerve agent. Expand
The interaction of sarin and soman with plasma proteins: the identification of a novel phosphonylation site
Incubation of both sarin and soman with human plasma has shown that binding occurs to a tyrosine residue, which may provide an important biological marker, which retains full structural information concerning the identity of the agent, in cases of allegations of chemical warfare use. Expand
Biomarkers of organophosphorus nerve agent exposure: comparison of phosphylated butyrylcholinesterase and phosphylated albumin after oxime therapy
Plasma samples obtained from an animal study aimed at improving therapy against nerve agent poisoning were used to compare the suitability of tyrosine and butyrylcholinesterase (BuChE) adducts as biomarkers of nerve agent exposure after treatment with therapeutic oximes. Expand
Analysis of β-Lyase Metabolites of Sulfur Mustard in Urine by Electrospray Liquid Chromatography-Tandem Mass Spectrometry
A method is described for the analysis of b-lyase metabolites of sulfur mustard, 1-methylsulfinyl-2- [2-(methylthio)ethylsulfonyl]ethane and 1,1'-sulfonylbis [2-(methylsulfinyl)ethane], in humanExpand
West Nile Virus Encephalitis in a Dog
In November 2002, a 2-year-old, spayed Maltese Terrier in central Mississippi was presented for an acute illness characterized by uncontrolled hyperactivity that rapidly progressed to generalized tremors, ataxia, and intermittent hyperthermia, which is consistent with acute encephalitis due to WNV infection. Expand
Analysis of degradation products of organophosphorus chemical warfare agents and related compounds by liquid chromatography–mass spectrometry using electrospray and atmospheric pressure chemical
Abstract A qualitative screening procedure was developed for the detection and identification of phosphonic acid hydrolysis products of organophosphorus chemical warfare agents, using liquidExpand
Biological fate of sulfur mustard, 1,1'-thiobis(2-chloroethane). Urinary excretion profiles of hydrolysis products and beta-lyase metabolites of sulfur mustard after cutaneous application in rats.
The excretion of beta-lyase products showed a much sharper decline than was observed for the hydrolysis products of sulfur mustard, and was reduced to a common analyte, 1,1'-sulfonylbis-[2-(methylthio)ethane], after similar treatment with titanium trichloride. Expand