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Flowering Plants of Jamaica
The exploration and knowledge of the flora and vegetation of the West Indies ran far ahead of that of many countries much closer to the great historical centers of systematic botany mainly because…
Flowering Plants of Jamaica.
A REVISED CLASSIFICATION OF FOSSIL PALM AND PALM‐LIKE LEAVES
The interaction of sarin and soman with plasma proteins: the identification of a novel phosphonylation site
Incubation of both sarin and soman with human plasma has shown that binding occurs to a tyrosine residue, which may provide an important biological marker, which retains full structural information concerning the identity of the agent, in cases of allegations of chemical warfare use.
Phosphylated tyrosine in albumin as a biomarker of exposure to organophosphorus nerve agents
- Nicholas H Williams, J. Harrison, R. Read, R. Black
- Medicine, BiologyArchives of Toxicology
- 8 March 2007
The tyrosine adducts with soman and tabun were detected in guinea pigs receiving therapy 7 days following subcutaneous administration of five times the LD50 dose of the respective nerve agent.
Application of gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry to the analysis of chemical warfare samples, found to contain residues of the nerve agent sarin,…
Biomarkers of organophosphorus nerve agent exposure: comparison of phosphylated butyrylcholinesterase and phosphylated albumin after oxime therapy
- R. Read, J. Riches, Jacqueline A. Stevens, S. Stubbs, R. Black
- Biology, MedicineArchives of Toxicology
Plasma samples obtained from an animal study aimed at improving therapy against nerve agent poisoning were used to compare the suitability of tyrosine and butyrylcholinesterase (BuChE) adducts as biomarkers of nerve agent exposure after treatment with therapeutic oximes.
Biological fate of sulphur mustard, 1,1'-thiobis(2-chloroethane): identification of beta-lyase metabolites and hydrolysis products in human urine.
No background levels of beta-lyase metabolites have been detected in normal human urine, and they are proposed as unequivocal diagnostic and forensic indicators of sulphur mustard poisoning in man.
Analysis of 1,1'-sulphonylbis[2-(methylsulphinyl)ethane] and 1-methylsulphinyl-2-[2-(methylthio)ethylsulphonyl]ethane, metabolites of sulphur mustard, in urine using gas chromatography-mass…
Analysis of β-Lyase Metabolites of Sulfur Mustard in Urine by Electrospray Liquid Chromatography-Tandem Mass Spectrometry
A method is described for the analysis of b-lyase metabolites of sulfur mustard, 1-methylsulfinyl-2- [2-(methylthio)ethylsulfonyl]ethane and 1,1'-sulfonylbis [2-(methylsulfinyl)ethane], in human…