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BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model.
Excitatory GABA actions, induced by altered expression of chloride transporters (KCC2/NKCC1), can contribute to seizure generation in temporal lobe epilepsy. In the present study, we evaluatedExpand
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Congenital Absence of the Posterior Element of C1, C2, and C3 Along with Bilateral Absence of C4 Pedicles: Case Report and Review of the Literature.
BACKGROUND Abnormalities of the posterior arch of vertebrae are rare conditions that may incidentally be found on neck radiographs. We report a case and present a comprehensive review of theExpand
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Demyelination with preferential MAG loss: A complex message from MS paraffin blocks
Multiple sclerosis (MS) is generally considered to be a demyelinating autoimmune disorder. However, neuropathological examinations of MS lesions do not support this concept. Demyelination withExpand
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B cells in multiple sclerosis therapy—A comprehensive review
For decades, B cells were ignored in multiple sclerosis (MS) pathogenesis, and the disease was always regarded as a T cell‐mediated disorder. Recent evidence shows that there is an antigen‐drivenExpand
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Multiple sclerosis pathogenesis: missing pieces of an old puzzle
Abstract Traditionally, multiple sclerosis (MS) was considered to be a CD4 T cell-mediated CNS autoimmunity, compatible with experimental autoimmune encephalitis model, which can be characterized byExpand
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Effect of bumetanide, a selective NKCC1 inhibitor, on hallucinations of schizophrenic patients; a double-blind randomized clinical trial
Hallucinations are a debilitating symptom of schizophrenia and can extremely influence the life quality of patients. A considerable percentage of schizophrenia patients suffer from hallucinationsExpand
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Lack of the effect of bumetanide, a selective NKCC1 inhibitor, in patients with schizophrenia: A double-blind randomized trial.
T HE EXCITATORY FUNCTION of GABA has been reported to contribute to the pathogenesis of some neuropsychological disorders, for example autism and epilepsy. The switch in GABA function, fromExpand
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Automated Detection and Segmentation of Multiple Sclerosis Lesions Using Ultra–High-Field MP2RAGE
Objectives The aim of this study was to develop a new automated segmentation method of white matter (WM) and cortical multiple sclerosis (MS) lesions visible on magnetization-prepared 2Expand
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Pilocytic Astrocytoma of Fornix Mimicking a Colloid Cyst: Report of 2 Cases and Review of the Literature.
BACKGROUND Colloid cyst is a gelatin-containing cyst in the brain almost always found in the third ventricle. The specific shape and location of these cysts, a round well-delineated mass in theExpand
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