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Characterization of OmpK, GAPDH and their fusion OmpK–GAPDH derived from Vibrio harveyi outer membrane proteins: their immunoprotective ability against vibriosis in large yellow croaker…
Aim: To investigate the immunoprotection of three recombinant proteins derived from the Vibrio harveyi outer membrane proteins (OMPs) OmpK, glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) and their…
[Clinical observation on effect of danzhi xiaoyao powder in treating depression].
- He-chun Luo, R. Qian, Shao-nan Yan
- Medicine, PsychologyZhongguo Zhong xi yi jie he za zhi Zhongguo…
- 1 March 2006
DXP shows the effect equivalent to that of maprotiline, but with obviously less side-effect, and scores of HAMD, SDS, SAS, and TCM-SSD of both groups were remarkably lowered after therapy.
Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance.
[Effect of Danzhi Xiaoyao Powder on neuro-immuno-endocrine system in patients with depression].
DXP is effective in improving symptoms of depression by regulating the levels of 5-HT, BDNF, CORT and IL-6.
[Study on free radical mechanism of guanxin II in antagonizing ischemic myocardial damage].
- Zhen-Yu Wang, R. Qian, Shuangxian Guan
- Medicine, BiologyZhongguo Zhong xi yi jie he za zhi Zhongguo…
- 1 May 2003
One of the molecular mechanisms of Guanxin II and its constituents in antagonizing and repairing myocardial damage is to scavenge the abnormal increased active OFR in tissue.
Kirenol upregulates nuclear annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats.
Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells.
[Study on therapeutic mechanism of anti-rheumatism action of herba siegesbeckiae].
Through regulating the immune function of organism, AFHS could improve the local pathologic response so as to antagonise against rheumatism, therefore, it is a good anti-rheUMatism herbal medicine.
A rapid and simple RP-HPLC method for quantification of kirenol in rat plasma after oral administration and its application to pharmacokinetic study.
- Xiao-Li Song, Qingying Zhang, Zhe-Ming Wang, H. Fu, R. Qian
- Chemistry, BiologyBiomedical chromatography : BMC
- 1 May 2011
A rapid and simple reverse-phase high-performance liquid chromatography (RP-HPLC) was developed and validated and successfully applied to the pharmacokinetic study of kirenol in male Sprague-Dawley rats after oral administration at a dose of 50 mg/kg.
Protective effects of 3,4-dihydroxyphenyl lactic acid on lipopolysaccharide-induced cerebral microcirculatory disturbance in mice.
Treatment with DLA significantly ameliorated LPS-induced insults in mice, including cerebral microcirculatory disturbance, the expression of CD11b/CD18 on neutrophils, and the increased concentration of plasma TNF-α and the production of T NF-α from mononuclear cells.