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Characterization of OmpK, GAPDH and their fusion OmpK–GAPDH derived from Vibrio harveyi outer membrane proteins: their immunoprotective ability against vibriosis in large yellow croaker…
Aim:  To investigate the immunoprotection of three recombinant proteins derived from the Vibrio harveyi outer membrane proteins (OMPs) OmpK, glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) and their…
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[Clinical observation on effect of danzhi xiaoyao powder in treating depression].
TLDR
DXP shows the effect equivalent to that of maprotiline, but with obviously less side-effect, and scores of HAMD, SDS, SAS, and TCM-SSD of both groups were remarkably lowered after therapy.
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Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance.
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[Effect of Danzhi Xiaoyao Powder on neuro-immuno-endocrine system in patients with depression].
TLDR
DXP is effective in improving symptoms of depression by regulating the levels of 5-HT, BDNF, CORT and IL-6.
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[Study on free radical mechanism of guanxin II in antagonizing ischemic myocardial damage].
TLDR
One of the molecular mechanisms of Guanxin II and its constituents in antagonizing and repairing myocardial damage is to scavenge the abnormal increased active OFR in tissue.
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Kirenol upregulates nuclear annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats.
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Shikonin, an ingredient of Lithospermum erythrorhizon, down-regulates the expression of steroid sulfatase genes in breast cancer cells.
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[Study on therapeutic mechanism of anti-rheumatism action of herba siegesbeckiae].
TLDR
Through regulating the immune function of organism, AFHS could improve the local pathologic response so as to antagonise against rheumatism, therefore, it is a good anti-rheUMatism herbal medicine.
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A rapid and simple RP-HPLC method for quantification of kirenol in rat plasma after oral administration and its application to pharmacokinetic study.
TLDR
A rapid and simple reverse-phase high-performance liquid chromatography (RP-HPLC) was developed and validated and successfully applied to the pharmacokinetic study of kirenol in male Sprague-Dawley rats after oral administration at a dose of 50 mg/kg.
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Protective effects of 3,4-dihydroxyphenyl lactic acid on lipopolysaccharide-induced cerebral microcirculatory disturbance in mice.
TLDR
Treatment with DLA significantly ameliorated LPS-induced insults in mice, including cerebral microcirculatory disturbance, the expression of CD11b/CD18 on neutrophils, and the increased concentration of plasma TNF-α and the production of T NF-α from mononuclear cells.
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