• Publications
  • Influence
Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
CONTEXT Despite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain. OBJECTIVE To assess the majorExpand
  • 13,551
  • 343
  • PDF
Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial.
CONTEXT Despite decades of use and considerable research, the role of estrogen alone in preventing chronic diseases in postmenopausal women remains uncertain. OBJECTIVE To assess the effects onExpand
  • 4,017
  • 98
  • PDF
The Statistical Analysis of Failure Data
[1] W. A. Rutledge, "Models for the reliability of memory With ECC", Proc. Expand
  • 825
  • 96
Surrogate endpoints in clinical trials: definition and operational criteria.
I discuss the idea of using surrogate endpoints in the context of clinical trials to compare two or more treatments or interventions in respect to some 'true' endpoint, typically a diseaseExpand
  • 1,631
  • 80
Logistic disease incidence models and case-control studies
SUMMARY The probability of disease development in a defined time period is described by a logistic regression model. A model for the regression variable, given disease status, is induced and isExpand
  • 1,065
  • 75
A case-cohort design for epidemiologic cohort studies and disease prevention trials
SUMMARY Suppose that a cohort of individuals is to be followed in order to relate failure rates to preceding covariate histories. A design is proposed which involves covariate data only for casesExpand
  • 1,228
  • 70
  • PDF
Correlated binary regression with covariates specific to each binary observation.
  • R. Prentice
  • Mathematics, Medicine
  • Biometrics
  • 1 December 1988
Regression methods are considered for the analysis of correlated binary data when each binary observation may have its own covariates. It is argued that binary response models that condition on someExpand
  • 833
  • 62
Calcium plus vitamin D supplementation and the risk of fractures.
BACKGROUND The efficacy of calcium with vitamin D supplementation for preventing hip and other fractures in healthy postmenopausal women remains equivocal. METHODS We recruited 36,282Expand
  • 1,653
  • 46
  • PDF