R. Ponsford

Publications48
h-index13
Citations525
Highly Influential Citations4
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In vitro antibacterial properties of BRL 36650, a novel 6 alpha-substituted penicillin
BRL 36650 is a new type of penicillin in which a formamido group has been introduced into the 6 alpha-position of the nucleus. The compound is highly active against aerobic gram-negative bacteria and…
Synthesis of cannabinoids by pyridine-catalysed citral–olivetol condensation: synthesis and structure of cannabicyclol, cannabichromen, (hashish extractives), citrylidene-cannabis, and related…
Citral condenses with olivetol in the presence of pyridine (1 mol) to give citrylidene-cannabis(III)(26%), cannabi-chromen (IV)(15%), its isomer (V)(3%) the bischromen (II)(6%), cannabicyclol…
Recent advances in the chemistry of anti-infective agents
TLDR
The chemistry of antibacterials/antibiotics chemistry of antifungals chemistry of antivirals and antiparasitics and the role of these compounds in medicine is studied.
COMPARISONS OF THERAPEUTIC EFFECTS OF LEVODOPA, LEVODOPA AND SELEGILINE, AND BROMOCRIPTINE IN PATIENTS WITH EARLY, MILD PARKINSONS-DISEASE - 3-YEAR INTERIM-REPORT
Intramolecular Wittig reactions with thioesters: the synthesis of 7-oxo-3-phenylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylates
4-Carboxymethylazetidin-2-ones have been converted into phenylthioesters and then into the 7-oxo-3-phenylthio-l-azabicyclo[3.2.0]hept-2-ene ring system via an intramolecular Wittig reaction.
Hashish components. Photochemical production of cannabicyclol from cannabichromene.
Synthesis of hashish cannabinoids by terpenic cyclisation
Clavulanic acid and its derivatives. Structure elucidation of clavulanic acid and the preparation of dihydroclavulanic acid, isoclavulanic acid, esters and related oxidation products
Clavulanic acid, a novel β-lactamase inhibitor from Streptomyces clavuligerus, has been shown to be Z-(2R,5R)-3-(β-hydroxyethylidene)-7-oxo-4-oxa-1 -azabicyclo[3.2.0]heptane-2-carboxylic acid (1).…
Structure-activity relationships of some 6 alpha-formamido penicillins.
Studies on semi-synthetic 7 alpha-formamidocephalosporins. I. Structure-activity relationships in some semi-synthetic 7 alpha-formamidocephalosporins.
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