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A Temperament Theory of Personality Development
Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia
It is estimated that 8,300 independent, mostly common SNPs contribute to risk for schizophrenia and that these collectively account for at least 32% of the variance in liability.
Temperament: Early Developing Personality Traits
1. Introduction 2. Evolution and Development 3. The Pediatric Approach 4. Arousal 5. Emotionality 6. Sociability 7. Theory and Measurement of EAS 8. Behavioral Genetics 9. Heredity and the EAS…
- R. Plomin
- PsychologyResearch publications - Association for Research…
From the combination of knowledge and actions, someone can improve their skill and ability, which will lead them to live and work much better and this behavioral genetics tells you.
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Moderate powered genome-wide association studies (GWAS) have enabled more than 20 additional risk loci to be identified and have shown that multiple variants exerting modest individual effects have a key role in disease susceptibility.
Gene–environment interaction analysis of serotonin system markers with adolescent depression
There was a significant genotype–environmental risk interaction for 5HTTLPR in female subjects only, with the effect being in the same direction as another recent study, reaffirming that an important source of genetic heterogeneity is exposure to environmental risk.
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
A new genome-wide association study of schizophrenia is reported, and through meta-analysis with existing data and integrating genomic fine-mapping with brain expression and chromosome conformation data, 50 novel associated loci and 145 loci are identified.
Roundtable: what is temperament? Four approaches.
Theorists representing 4 positions--Goldsmith, Buss and Plomin, Rothbart, and Thomas and Chess--outline their views by responding to each of 6 questions on the definition of temperament.
Parental feeding style and the inter-generational transmission of obesity risk.
- J. Wardle, S. Sanderson, C. Guthrie, L. Rapoport, R. Plomin
- Psychology, MedicineObesity Research
- 1 June 2002
The results suggest that the stereotype of the obese mother, who uses food in nonnutritive ways so that her child also becomes obese, is more likely to be myth than fact, but the results raise the possibility that lack of control of food intake might contribute to the emergence of differences in weight.
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
It is shown that polymorphisms of ERAP1, which encodes an endoplasmic reticulum aminopeptidase involved in peptide trimming before HLA class I presentation, only affect ankylosing spondylitis risk in HLA-B27–positive individuals.