Antidepressant medications and other treatments of depressive disorders: a CINP Task Force report based on a review of evidence.
- N. Sartorius, T. Baghai, A. Riecher-Rössler
- Psychology, MedicineInternational Journal of Neuropsychopharmacology
- 1 December 2007
The Task Force on Antidepressant Medications was established to examine all aspects of therapy with antidepressant drugs and to provide mental health and other professionals with comprehensive and objective information about the different aspects of the use of antidepressants important in clinical practice.
Treatment of generalized anxiety disorder
- R. Pinder
- PsychologyNeuropsychiatric Disease and Treatment
- 1 April 2007
Efficacy in anxiety disorders is not confined to SSRIs, however, and most antidepressants, particularly but not exclusively those with a serotonergic arm to their pharmacology, are in fact anxiolytic – in the previous issue of the journal, the efficacy of the SNRI venlafaxine in panic disorder was reviewed.
Structure-activity relationships in psychotomimetic phenylalkylamines.
Recrystallization from 95% ethanol to give a crystalline product, 1.08 g (46.5%), mp 110-113”, giving a thick oil which solidified in methanol.
Neurochemical and autonomic pharmacological profiles of the 6-aza-analogue of mianserin, org 3770 and its enantiomers
Carbenoxolone: A Review of its Pharmacological Properties and Therapeutic Efficacy in Peptic Ulcer Disease
Carbenoxolone is of greatest benefit in accelerating the healing of gastric ulcers in patients for whom hospitalisation is not possible or desirable, but it should only be used in the ambulatory patient when careful and regular observation of serum electrolytes, blood pressure and weight is possible and when it is known that the patient will attend regular follow-up.
Miconazole: A Review of its Antifungal Activity and Therapeutic Efficacy
Preliminary experience with oral and intravenous miconazole therapy in systemic candidiasis is promising, and the vaginal cream has produced higher cure rates than conventional nystatin vaginal tablets or amphotericin B vaginal cream, and there have been no published comparisons with other antifungal agents.
Designing a new generation of antidepressant drugs
- R. Pinder
- Psychology, BiologyActa Psychiatrica Scandinavica Supplementum
- 1 September 1997
Mirtazapine, the prototype noradrenergic and specific serotonergic antidepressant (NaSSA), specifically enhances 5‐HT, neurotransmission and blocks 5-HT2 and 5‐ HT3 receptors, and in contrast to venlafaxine lacks SSRI‐like and adverse cardiovascular side effects.
The benefits and risks of antidepressant drugs
- R. Pinder
- Psychology, Medicine
- 1 June 1988
Most antidepressants currently available have broadly equal efficacy, although some drugs may be more appropriate in certain types of patient, when particular symptoms are prominent or when a particular side‐effect is undesirable.
Fenfluramine: a review of its pharmacological properties and therapeutic efficacy in obesity.
The majority of patients tolerate fenfluramine satisfactorily, although some patients may have to discontinue the drug because of troublesome gastro-intestinal problems, diarrhoea, drowsiness or dizziness, and it probably has little abuse potential.