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Multicenter randomized trial comparing tacrolimus (FK506) and cyclosporine in the prevention of renal allograft rejection: a report of the European Tacrolimus Multicenter Renal Study Group.
BACKGROUND To confirm the results of a number of studies conducted in Europe, the United States, and Japan, this multicenter, randomized trial compared the 12-month efficacy and safety of tacrolimus-Expand
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Recurrence patterns of hepatocellular and fibrolamellar carcinoma after liver transplantation.
PURPOSE Tumor recurrence is the major limitation of long-term survival after liver transplantation for hepatocellular carcinoma (HCC) or fibrolamellar carcinoma (FLC). Understanding tumor-biologicExpand
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Drug metabolism in hepatocyte sandwich cultures of rats and humans.
Adult hepatocytes from rat and man were maintained for 2 weeks between two gel layers in a sandwich configuration to study the influence of this culture technique on the preservation of basalExpand
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Monoclonal antibody therapy for resected Dukes' C colorectal cancer: seven-year outcome of a multicenter randomized trial.
PURPOSE As previously shown, antibody treatment increased survival of patients with resected colorectal cancer of stage Dukes' C. Since the 5-year analysis was criticized because of the wide rangeExpand
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Expression of hepatitis B virus X protein in HBV‐infected human livers and hepatocellular carcinomas
Transactivation of cellular genes and functional inactivation of p53 by the hepatitis B virus (HBV) X gene‐encoded protein (HBx) are proposed as alternative mechanisms for induction of hepatocellularExpand
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Identification of high‐ and low‐risk patients before liver transplantation: A prospective cohort study of nutritional and metabolic parameters in 150 patients
The clinical relevance of malnutrition and hypermetabolism in end‐stage liver disease, as well as their effects on survival after liver transplantation (LTx), are largely unknown. This studyExpand
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Surgical treatment of hepatocellular carcinoma: Experience with liver resection and transplantation in 198 patients
Surgical therapy offers the only chance for long-term cure of patients with hepatocellular carcinoma. The role of partial and total hepatectomy with subsequent liver replacement was analyzed in aExpand
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Benign Liver Tumors: Differential Diagnosis and Indications for Surgery
Abstract. The differential diagnosis for hemangioma, focal nodular hyperplasia (FNH), and hepatocellular adenoma may be difficult. Reliable diagnosis is mandatory for the decision of whether to applyExpand
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Kidney transplanted children come of age.
BACKGROUND The aim of renal replacement therapy in children is to restore their potential for normal growth and development in order to reach mature adulthood. Because pediatric kidneyExpand
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Surgical treatment in proximal bile duct cancer. A single-center experience.
OBJECTIVES The authors evaluated the experience and results of a single center in surgical treatment of proximal bile duct carcinoma. SUMMARY BACKGROUND DATA Whenever feasible, surgery is theExpand
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