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CFTR Expression in human neutrophils and the phagolysosomal chlorination defect in cystic fibrosis.
TLDR
Evidence is provided which suggests that CFTR channel expression in neutrophils and its dysfunction affect neutrophil chlorination of phagocytosed bacteria.
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Signal transduction and cytoskeletal activation in the neutrophil.
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The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.
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Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis.
TLDR
It is found that MSCs possess the capacity of differentiating into airway epithelia, and the ex vivo coculture system established in this report offers an invaluable approach for selection of stem-cell populations that may have greater potency in lung differentiation.
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Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils
TLDR
The data demonstrate the possibility of pharmacologic correction of impaired recruitment of mutant CFTR, thereby providing a potential means to augment chloride supply to the phagosomes of PMN in patients with cystic fibrosis to enhance their microbicidal function.
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Anionic sites of human erythrocyte membranes. II. Antispectrin-induced transmembrane aggregation of the binding sites for positively charged colloidal particles.
TLDR
Results were interpreted as evidence for a structural transmembrane linkage between the inner surface peripheral protein spectrin and the integral membrane component glycophorin.
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Relationship of actin polymerization and depolymerization to light scattering in human neutrophils: dependence on receptor occupancy and intracellular Ca++
TLDR
It is suggested that transient actin polymerization and transient cell ruffling give rise to transient aggregation as long as degranulation is limited and may be somewhat sensitive to the availability of intracellular Ca++.
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Thrombin increases expression of fibronectin antigen on the platelet surface.
TLDR
Thrombin stimulation results in increased expression of fn antigen on the platelet surface, and here it may participate in interactions with fibrin, connective tissue, or other cells.
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Function of neutral endopeptidase on the cell membrane of human neutrophils.
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Effect of concanavalin A on expression of cell surface sialyltransferase activity of mouse thymocytes.
  • R. Painter, A. White
  • Biology, Chemistry
    Proceedings of the National Academy of Sciences…
  • 1 March 1976
TLDR
Alterations in sialyltransferase activity due to concanavalin A treatment could not be explained by a mitogen-mediated uptake of radioactive precursors, cell death, increased product catabolism, or activation of sialYLtransferase by mitogen binding to the enzyme.
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