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Innate and adaptive immunity in atherosclerosis
Atherosclerosis, a chronic inflammatory disorder, involves both the innate and adaptive arms of the immune response that mediate the initiation, progression, and ultimate thrombotic complications ofExpand
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Cardiac PET perfusion tracers: current status and future directions.
PET myocardial perfusion imaging (MPI) is increasingly being used for noninvasive detection and evaluation of coronary artery disease. However, the widespread use of PET MPI has been limited by theExpand
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Absolute Quantitation of Myocardial Blood Flow in Human Subjects With or Without Myocardial Ischemia Using Dynamic Flurpiridaz F 18 PET
Absolute quantitation of myocardial blood flow (MBF) by PET is an established method of analyzing coronary artery disease (CAD) but subject to the various shortcomings of available radiotracers.Expand
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Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains
Common forms of atherosclerosis involve multiple genetic and environmental factors. While human genome-wide association studies have identified numerous loci contributing to coronary artery diseaseExpand
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PET should replace SPECT in cardiac imaging for diagnosis and risk assessment of patients with known or suspected CAD: Pro
Positron emission tomography (PET) myocardial perfusion imaging (MPI) has been performed for the better part of 3 decades. Initially limited to academic centers and viewed with skepticism, it hasExpand
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Accuracy of stress myocardial perfusion imaging to diagnose coronary artery disease in end stage liver disease patients.
Patients with end-stage liver disease (ESLD) who also have underlying coronary artery disease (CAD) may be at increased risk for undergoing hemodynamically challenging orthotopic liverExpand
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Automated Segmentation of Light-Sheet Fluorescent Imaging to Characterize Experimental Doxorubicin-Induced Cardiac Injury and Repair
This study sought to develop an automated segmentation approach based on histogram analysis of raw axial images acquired by light-sheet fluorescent imaging (LSFI) to establish rapid reconstruction ofExpand
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Spatial and temporal variations in hemodynamic forces initiate cardiac trabeculation.
Hemodynamic shear force has been implicated as modulating Notch signaling-mediated cardiac trabeculation. Whether the spatiotemporal variations in wall shear stress (WSS) coordinate the initiation ofExpand
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Fractional flow reserve by computerized tomography and subsequent coronary revascularization
Aims Fractional flow reserve by computerized tomography (FFR-CT) provides non-invasive functional assessment of the hemodynamic significance of coronary artery stenosis. We determined the FFR-CTExpand
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Inductively powered wireless pacing via a miniature pacemaker and remote stimulation control system
We demonstrated a remote-controlled miniaturized pacing system in which power requirements were significantly reduced via intermittent power transfer to control stimulation intervals. Expand
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