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Tranexamic acid (Cyklokapron) is not necessary to reduce blood loss after coronary artery bypass operations.
The contribution of fibrinolysis to postoperative bleeding after cardiopulmonary bypass led to routine use of tranexamic acid, a potent antifibrinolytic drug, for a period of time. Two hundredExpand
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Conventional blood conservation techniques in 500 consecutive coronary artery bypass operations.
With use of a nonpharmacological, simple, and inexpensive program for blood conservation, 500 consecutive patients underwent elective coronary artery bypass grafting without need of homologous redExpand
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Comparison of two heparin-coated extracorporeal circuits with reduced systemic anticoagulation in routine coronary artery bypass operations.
OBJECTIVES The use of heparin-coated circuits for cardiopulmonary bypass attenuates the postperfusion inflammatory response. Postoperative bleeding and the need for allogeneic blood transfusions areExpand
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Autotransfusion in coronary artery bypass grafting: disparity in laboratory tests and clinical performance.
OBJECTIVE Autotransfusion during and after cardiac surgery is widely performed, but its effects on coagulation, fibrinolysis, and inflammatory response have not been known in detail. METHODSExpand
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Completely heparinized cardiopulmonary bypass and reduced systemic heparin: clinical and hemostatic effects.
BACKGROUND When heparinized circuits are used for cardiopulmonary bypass, the amounts of heparin and protamine administered systemically can be reduced. However, it is not entirely known what effectsExpand
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Complement and granulocyte activation in two different types of heparinized extracorporeal circuits.
Complement and granulocyte activation were studied in cardiopulmonary bypass circuits completely coated with either end-attached covalent-bonded heparin, the Carmeda BioActive Surface, or with theExpand
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Complete heparin-coated cardiopulmonary bypass and low heparin dose reduce complement and granulocyte activation.
Complete heparin-coated extracorporeal circuits, including cardiotomy reservoir, have recently become available for routine cardiac surgery. The effects on complement and granulocyte activation usingExpand
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Complete heparin-coated (CBAS) cardiopulmonary bypass and reduced systemic heparin dose; effects on coagulation and fibrinolysis.
OBJECTIVE Heparin-coated extracorporeal circuits allow reduced amounts of systemic heparin and protamine. However, the effects on the coagulation and fibrinolytic systems when reducing systemicExpand
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[Coronary surgery at the Heart Center in Oslo 1989-98].
BACKGROUND Coronary artery bypass grafting was performed in 5,658 consecutive patients during the period 1989-1998. Due to changes over time, both in patients' risk profile and surgical strategies, aExpand
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[Cost savings with autotransfusion in connection with coronary surgery].
The main purpose of this study was to estimate the costs and savings related to a consistent autotransfusion programme. More than 8,000,000 ml of autologous blood or blood-containing fluid wereExpand