• Publications
  • Influence
Bioassay-guided isolation of a vasorelaxant active compound from Kaempferia galanga L.
Bioassay-guided fractionation was performed on a crude dichloromethane extract of Kaempferia galanga L. using chromatography techniques. Screening of the extract for biological activity started withExpand
  • 57
  • 4
  • PDF
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and inExpand
  • 51
  • 4
  • PDF
Validation of Quantitative Structure-Activity Relationship (QSAR) Model for Photosensitizer Activity Prediction
Photodynamic therapy is a relatively new treatment method for cancer which utilizes a combination of oxygen, a photosensitizer and light to generate reactive singlet oxygen that eradicates tumors viaExpand
  • 26
  • 4
  • PDF
Vasorelaxant effects of ethyl cinnamate isolated from Kaempferia galanga on smooth muscles of the rat aorta.
From the rhizomes of Kaempferia galanga, ethyl cinnamate (EC) was isolated and its vasorelaxant effect was examined on the rat aorta. EC inhibited the tonic contractions induced by high K+ andExpand
  • 33
  • 3
Thymoquinone Induces Mitochondria-Mediated Apoptosis in Acute Lymphoblastic Leukaemia in Vitro
There has been a growing interest in naturally occurring compounds from traditional medicine with anti-cancer potential. Nigella sativa (black seed) is one of the most widely studied plants. ThisExpand
  • 58
  • 2
  • PDF
Computational identification of self‐inhibitory peptides from envelope proteins
Fusion process is known to be the initial step of viral infection and hence targeting the entry process is a promising strategy to design antiviral therapy. The self‐inhibitory peptides derived fromExpand
  • 128
  • 1
Rational Discovery of Dengue Type 2 Non‐Competitive Inhibitors
Various works have been carried out in developing therapeutics against dengue. However, to date, no effective vaccine or anti‐dengue agent has yet been discovered. The development of proteaseExpand
  • 28
  • 1
  • PDF
In vitro and in vivo anti-inflammatory activities of columbin through the inhibition of cycloxygenase-2 and nitric oxide but not the suppression of NF-κB translocation.
Columbin, a diterpenoid furanolactone, was isolated purely for the first time from the plant species Tinspora bakis. The anti-inflammatory effects of columbin were studied in vitro, in silico and inExpand
  • 19
  • 1
  • PDF
Thymoquinone Inhibits Murine Leukemia WEHI-3 Cells In Vivo and In Vitro
Background Thymoquinone is an active ingredient isolated from Nigella sativa (Black Seed). This study aimed to evaluate the in vitro and in vivo anti-leukemic effects of thymoquinone on WEHI-3 cells.Expand
  • 25
  • 1
  • PDF
Synthesis, Characterization, X-ray Crystallography, Acetyl Cholinesterase Inhibition and Antioxidant Activities of Some Novel Ketone Derivatives of Gallic Hydrazide-Derived Schiff Bases
Alzheimer’s disease (AD) is the most common form of dementia among older people and the pathogenesis of this disease is associated with oxidative stress. Acetylcholinesterase inhibitors withExpand
  • 24
  • 1
  • PDF
...
1
2
3
4
5
...