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The α7β0 Isoform of the Complement Regulator C4b-Binding Protein Induces a Semimature, Anti-Inflammatory State in Dendritic Cells
The classical pathway complement regulator C4b-binding protein (C4BP) is composed of two polypeptides (α- and β-chains), which form three plasma oligomers with different subunit compositions (α7β1,Expand
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The Complement Inhibitor Factor H Generates an Anti-Inflammatory and Tolerogenic State in Monocyte-Derived Dendritic Cells
The activation of the complement system is a key initiating step in the protective innate immune-inflammatory response against injury, although it may also cause harm if left unchecked. TheExpand
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CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling.
The CD40-CD154 dyad seems to play a prominent role fostering the immune-inflammatory response triggered by endothelial cell (EC)-T-cell communication. To delineate comprehensively the involvement ofExpand
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In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection
The humoral branch of the immune response has an important role in acute and chronic allograft dysfunction. The CD40/CD40L costimulatory pathway is crucial in B- and T- alloresponse. Our group hasExpand
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Assessment of Human Dendritic Cell Antigen Uptake by Flow Cytometry
[Abstract] Antigen uptake by dendritic cells is the first key step towards induction of antigenspecific T-cell responses. This flow cytometry-based protocol describes the analysis of dendritic cellExpand
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This information is current as Dendritic Cells Semimature , Anti-Inflammatory State in Regulator C 4 b-Binding Protein Induces a Isoform of the Complement 0 β 7 α The Rodríguez de Córdoba
The classical pathway complement regulator C4b-binding protein (C4BP) is composed of two polypeptides (a-and b-chains), which form three plasma oligomers with different subunit compositions (a 7 b 1Expand