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Caffeic Acid Derivatives: In Vitro and In Vivo Anti-inflammatory Properties
TLDR
Results confirm and extend literature data, showing that caffeic acid derivatives exert in vitro and in vivo anti-inflammatory actions, being their actions mediated, at least in part by the scavenging of NO and their ability to modulate iNOS expression and probably that of other inflammatory mediators. Expand
A review of the ethnopharmacology, phytochemistry and pharmacology of plants of the Maytenus genus.
TLDR
This review summarizes the ethnopharmacological, chemical and pharmacological knowledge of plants of the Maytenus genus, with particular emphasis on those growing in Brazil. Expand
Evaluation of the relaxant action of some Brazilian medicinal plants in isolated guinea-pig ileum and rat duodenum.
TLDR
It is suggested that, of the six medicinal plants evaluated, only the ME of Calophyllum brasiliense and Cynara scolymus show probable antispasmodic activity, confirming and justifying their use in folk medicine for the treatment of intestinal disorders. Expand
Antinociceptive properties of caffeic acid derivatives in mice.
TLDR
Dodecyl ester derivative exhibited potent and dose-related activity against the writhing test, and appears to support its therapeutic potential against painful diseases. Expand
Gastroprotective activity of hydroalcoholic extract obtained from the leaves of Brassica oleracea var. acephala DC in different animal models.
TLDR
The data suggest that the effectiveness of hydroalcoholic extract of Brassica oleracea is based on its ability to stimulate the synthesis of mucus, increase pH and decrease H(+) ions in the stomach, as demonstrated by the significant inhibition of ulcer formation induced using different models. Expand
Evaluation of Antileishmanial Activity of Selected Brazilian Plants and Identification of the Active Principles
TLDR
Plant extracts, fractions, and isolated compounds from some selected Brazilian medicinal plants against strains of promastigotes of Leishmania amazonensis and L. brasiliensis are concluded that the analyzed plants are promising as new and effective antiparasitic agents. Expand
Antiulcerogenic activity of fractions and 3,15-Dioxo-21α-hydroxy friedelane isolated from Maytenus robusta (Celastraceae)
TLDR
The result suggests that the antiulcer effect observed in the extract and fractions may be attributed, at least in part, to this compound. Expand
Antinociceptive properties of steroids isolated from Phyllanthus corcovadensis in mice.
TLDR
Findings suggest that stigmasterol and beta-sitosterol may account, at least in part, for the antinociceptive actions reported previously for the hydroalcoholic extract of Phyllanthus corcovadensis. Expand
Analgesic triterpenes from Sebastiania schottiana roots.
TLDR
The results suggest that the roots of S. schottiana contain analgesic compounds which justify, at least partially, the popular use of this plant for the treatment of urinary problems. Expand
Pharmacological mechanisms underlying the anti-ulcer activity of methanol extract and canthin-6-one of Simaba ferruginea A. St-Hil. in animal models.
TLDR
The efficacy of MESf and Cant in gastroprotection shows that Simaba ferruginea might be a promising antiulcer herbal medicine, in addition to confirming the popular use of this plant against gastric ulcer models utilised in this study. Expand
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