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DAI-10 is as good as DAI-30 in schizophrenia
TLDR
DAI is an easy-to-use self-report instrument seemingly assessing a unique clinical dimension relevant to non-adherence in first-episode schizophrenia and might be preferred for its simplicity and good psychometric properties. Expand
Changes in the diagnosed incidence of early onset schizophrenia over four decades
TLDR
The diagnosed incidence of early onset schizophrenia (EOS) from 1971 to 2010 is studied to explore changes in the diagnosed incidence. Expand
Clinical use of lithium salts: guide for users and prescribers
TLDR
Recommendations concerning safe clinical use of lithium salts to treat major mood disorders, including indications, dosing, clinical monitoring, adverse effects and use in specific circumstances including during pregnancy and for the elderly are summarized. Expand
Predictors of Clozapine Response in Patients With Treatment-Refractory Schizophrenia: Results From a Danish Register Study
TLDR
Although the study design does not allow any causal inferences, all 3 models suggested a lower number of psychiatric hospitalizations and antipsychotic trials before clozAPine initiation to be associated with greater clozapine response. Expand
What is the optimal serum level for lithium in the maintenance treatment of bipolar disorder? A systematic review and recommendations from the ISBD/IGSLI Task Force on treatment with lithium
To systematically review the existing trials on optimal serum levels for lithium for maintenance treatment of bipolar disorder and to develop clinical recommendations.
Type 2 Diabetes Mellitus in Youth Exposed to Antipsychotics: A Systematic Review and Meta-analysis.
TLDR
Although T2DM seems rare in antipsychotic-exposed youth, cumulative risk and exposure-adjusted incidences and IRRs were significantly higher than in healthy controls and psychiatric controls. Expand
Increasing mortality gap for patients diagnosed with schizophrenia over the last three decades — A Danish nationwide study from 1980 to 2010
TLDR
On average, patients with schizophrenia die younger than the general population, independent of intentional self-harm as cause of death. Expand
Characteristics and predictors of long-term institutionalization in patients with schizophrenia
TLDR
Institutionalized patients with schizophrenia had a more complex and worse outcome of the disorder, except for less suicide, illustrated by lower scholastic achievement, receiving higher dosages of antipsychotic medications, more concomitant medications and more prior bed-days. Expand
Pharmacological treatment of unipolar depression during pregnancy and breast-feeding—A clinical overview
TLDR
This overview is aimed at clinicians working with patients in the fertile age who suffer from depressive disorders, and finds that citalopram and sertraline can be used during pregnancy, while some controversy remains over in utero exposure to paroxetines and fluoxetine, which might be associated with an increased risk of foetal cardiovascular malformation. Expand
Lithium’s antiviral effects: a potential drug for CoViD-19 disease?
TLDR
Lithium presents a clear antiviral activity demonstrated at preclinical level, but that remains to be confirmed in clinical settings, and the pleiotropic mechanisms of action of lithium may provide an insight for its possible use as antiviral agent targeting specific pathways. Expand
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