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Complete design of a simulated moving bed
Abstract The operating conditions of a simulated moving bed working under conditions of non-linear chromatography are difficult to find experimentally. A design procedure based on the modelling ofExpand
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The Amazing Ability of Continuous Chromatography To Adapt to a Moving Environment
While normally considered an expensive technology, chromatography has been used for very large-scale applications for ∼50 years. Main successes reported in the petrochemical or sugar industries areExpand
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The simulated moving bed A powerful process for purification
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Preparative scale enantioseparation of a chiral epoxide: Comparison of liquid chromatography and simulated moving bed adsorption technology
The feasibility of using simulated moving bed technology (SMB) for chiral separation on cellulose triacetate is demonstrated on the preparative scale: 1 kg of a chiral epoxide has been separated. OnExpand
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Chromatographic Processes: Modeling, Simulation, and Design
1. An approach to modeling chromatographic processes 2. Linear chromatography: the Russian Lego 3. Non-linear chromatography: equilibrium theory 4. Fluid-solid phase equilibria 5. Mass transfer 6.Expand
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Simulierte Gegenstromchromatographie: Eine effiziente Technik zur Herstellung optisch aktiver Verbindungen im industriellen Maßstab?: Simulierte Gegenstromchromatographie: Eine effiziente Technik zur
Since chiral stationary phase (CSP) become available for high-performance liquid chromatography (HPLC), preparative chromatography has been recognised more and more as an efficient tool in preparingExpand
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Purification of Difluoromethylornithine by Global Process Optimization: Coupling of Chemistry and Chromatography with Enantioselective Crystallization
An industrial process for the purification of metric tons of enantiomerically pure difluoromethylornithine (DFMO HCl) is described. The amino acid DFMO HCl is cyclized to form the lactam, which isExpand
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Comparing multi-column chromatographic processes for purifying monosaccharides part I: A simplified approach
This work proposes a methodology for comparing different multi-column chromatographic processes (SMB, ISMB, SSMB) for purifying monosaccharides. The first step of the methodology consists inExpand
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A continuum theory for multicomponent chromatography modeling.
A continuum theory is proposed for modeling multicomponent chromatographic systems under linear conditions. The model is based on the description of complex mixtures, possibly involving tens orExpand
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