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Discovery of a cholecystokinin-gastrin-like signaling system in nematodes.
TLDR
The data indicate that the gastrin-CCK signaling system was already well established before the divergence of protostomes and deuterostomes, and also display similar biological activities with respect to digestive enzyme secretion and fat storage.
Expression and Functional Characterization of aDrosophila Neuropeptide Precursor with Homology to Mammalian Preprotachykinin A*
TLDR
Analysis of the Drosophila genome allowed us to identify a putative tachykinin-related peptide prohormone (prepro-DTK) gene, which encodes five novel D rosophila tachyKinin- related peptides (called DTK peptides) with conserved C-terminal FXGXR-amide motifs common to other insect tachy Kinin-based peptides.
Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor
TLDR
To the authors' knowledge, the cloned DrmFMRFa-R is the first functionally active FMRFamide G protein-coupled receptor described in invertebrates to date.
Insect capa neuropeptides impact desiccation and cold tolerance
TLDR
It is demonstrated that the Drosophila melanogaster capa neuropeptide gene and its encoded peptides alter desiccation and cold tolerance and the use of rationally designed peptide analogs as agents for disrupting protective stress tolerance.
The neuropeptidomics of Ixodes scapularis synganglion.
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