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Role of AMP-activated protein kinase in mechanism of metformin action.
- G. Zhou, R. Myers, +11 authors D. Moller
- Chemistry, Medicine
- The Journal of clinical investigation
- 15 October 2001
Metformin is a widely used drug for treatment of type 2 diabetes with no defined cellular mechanism of action. Its glucose-lowering effect results from decreased hepatic glucose production and… Expand
The influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of myogenic progenitor cells ex vivo.
Skeletal muscle relies upon regeneration to maintain homeostasis and repair injury. This process involves the recruitment of the tissue's resident stem cell, the muscle progenitor cell, and a… Expand