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Correlates and Predictors of Adherence to Highly Active Antiretroviral Therapy: Overview of Published Literature
TLDR
This review summarizes the results of 20 studies investigating the issue of barriers to optimal highly active antiretroviral therapy (HAART) adherence and found inconsistent findings regarding the relationship of adherence.
Self‐Reported Symptoms and Medication Side Effects Influence Adherence to Highly Active Antiretroviral Therapy in Persons With HIV Infection
TLDR
In addition to patient characteristics, medication‐related variables, and reasons for nonadherence, patient‐reported symptoms and medication side effects were significantly associated with adherence to HAART.
Depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy among HIV-infected persons.
The association of depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy (HAART) was evaluated in 135 HIV-infected persons. Thirty percent reported
Determinants of health-related quality of life in HIV-infected patients
TLDR
Symptoms, recent hospitalization and satisfaction with information are most amenable to clinical intervention in a cohort of Italian HIV-infected patients.
Neurocognitive performance and quality of life in patients with HIV infection.
TLDR
Cognitive impairment in any cognitive domain explored in a battery of 17 neuropsychological tests is associated with poor QoL, and people with more severe cognitive impairment have the highest probability of having a poorQoL.
Depression Is a Risk Factor for Suboptimal Adherence to Highly Active Antiretroviral Therapy
TLDR
Early recognition and proper management of depressive comorbidity could be an effective intervention strategy to improve adherence and may make a difference in the quality of life, social functioning, and disease course of people with HIV.
AIDS-related focal brain lesions in the era of highly active antiretroviral therapy
TLDR
During the HAART era, AIDS-related primary CNS lymphoma showed a strong decline, toxoplasmic encephalitis remained stable, and progressive multifocal leukoencephalopathy showed a slight increase, and focal white matter lesions without mass effect or contrast enhancement became the most frequently seen focal brain lesion.
Value of combined approach with thallium-201 single-photon emission computed tomography and Epstein-Barr virus DNA polymerase chain reaction in CSF for the diagnosis of AIDS-related primary CNS
TLDR
Because PCNSL likelihood is extremely high in patients with hyperactive lesions and positive EBV-DNA, brain biopsy could be avoided, and patients could promptly undergo radiotherapy or multimodal therapy.
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