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Characterization of a novel transplantable orthotopic rat bladder transitional cell tumour model
The orthotopic AY-27 TCC model is highly reproducible and is ideal for preclinical studies on experimental intravesical therapies, and the changes seen on MRI correlated well with the extent of tumour invasion identified histologically.
Reconstitution of Ca(2+)-dependent K+ transport in erythrocyte membrane vesicles requires a cytoplasmic protein.
Effects of cadmium on respiration rate and activities of several enzymes in soybean seedlings
Soybean (Glycine max L. cv. Columbus) seedlings grown in culture solution were treated with cadmium as CdSO/sub 4/. Final concentrations of cadmium (Cd/sup 2 +/) in the solution were 0, 0.45, 0.90,…
Magnetic resonance imaging of bone marrow in sickle cell disease: clinical, hematologic, and pathologic correlations.
A longitudinal, prospective, controlled evaluation of magnetic resonance images (MRI) of long bones in sickle cell patients was undertaken simultaneously with assessment of clinical status and…
Calcium-activated potassium transport and high molecular weight forms of calpromotin.
Acetochlor-induced rat nasal tumors: further studies on the mode of action and relevance to humans.
- T. Green, R. Lee, M. J. Clapp
- Biology, ChemistryRegulatory toxicology and pharmacology : RTP
- 1 August 2000
This metabolic conversion could not be detected in 33 fresh human nasal tissue samples, supporting the earlier view that the acetochlor-induced rat nasal tumors do not represent a hazard for humans.
Light dosimetry using the P3 approximation.
- D. Dickey, R. Moore, D. C. Rayner, J. Tulip
- Physics, MedicinePhysics in medicine and biology
- 1 September 2001
The results demonstrate that the spherical derivation of the P3 approximation will reproducibly predict optical parameters of a tissue phantom as effectively as the slab geometry derivations of theP3 approximation.
Ascorbate protects against tert-butyl hydroperoxide inhibition of erythrocyte membrane Ca2+ + Mg2(+)-ATPase.
The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.
- M. Ellis, A. Richardson, G. A. Wickramaratne
- Biology, ChemistryToxicology and Applied Pharmacology
- 1 July 1998
In vitro, molinate is a poor inhibitor of esterase activity, whereas molinate sulfoxide, a major metabolite of molinate in rats, and molinated sulfone were shown to be potent inhibitors of this process, suggesting that metabolic activation of molinates is required in vivo.
Biodistribution of Photofrin II® and 5‐Aminolevulinic Acid‐Induced Protoporphyrin IX in Normal Rat Bladder and Bladder Tumor Models: Implications for Photodynamic Therapy
Intravesical administration of ALA or PII might be feasible for PDT of superficial bladder cancers, as evaluated in rats bearing orthotopic and heterotopic bladder tumor models.