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Synthetic cathinones: chemistry, pharmacology and toxicology of a new class of designer drugs of abuse marketed as "bath salts" or "plant food".
In 2000s, many synthetic cathinones have received a renewed popularity as designer drugs of abuse, particularly among young people. Despite being marketed as "bath salts" or "plant food" and labeled… Expand
3,4-methylenedioxypyrovalerone (MDPV): chemistry, pharmacology and toxicology of a new designer drug of abuse marketed online.
The illicit marketplace of substances of abuse continually offers for sale legal alternatives to controlled drugs to a large public. In recent years, a new group of designer drugs, the synthetic… Expand
Methoxetamine: from drug of abuse to rapid-acting antidepressant.
Methoxetamine is a dissociative anaesthetic showing pharmacodynamic similarities with its analogue ketamine, a medication with demonstrated rapid-acting antidepressant effects. Like ketamine and… Expand
Olanzapine blocks the sympathetic and hyperthermic reactions due to cerebral injection of orexin A
Since experiments regarding a possible relation between olanzapine and orexin A has been scarcely reported in international literature, this experiment tested the effect of olanzapine on the… Expand
AH-7921: a new synthetic opioid of abuse.
4,4'-DMAR: chemistry, pharmacology and toxicology of a new synthetic stimulant of abuse.
In recent years, the spread of new psychoactive substances has dramatically increased in term of availability of both number of compounds and chemical families. In November 2012,… Expand
Research chemicals marketed as legal highs: the case of pipradrol derivatives.
Between 1997 and 2011, more than 200 new substances were notified through the early-warning system, with the record number of 49 novel molecules reported in 2011. The pattern of acute toxicity… Expand
JWH-122 Consumption Adverse Effects: A Case of Hallucinogen Persisting Perception Disorder Five-Year Follow-Up
ABSTRACT Synthetic cannabinoid receptor agonists are a heterogeneous group of psychotropic drugs functionally related to Δ9-tetrahydrocannabinol. These substances, marketed as cannabis substitutes,… Expand
MT-45: a new, dangerous legal high.
Epidemiological data confirm that the use of new psychoactive substances is on the rise around the world.1 Numerous reports have described medical emergencies associated with the consumption of… Expand
Bromo-DragonFly: Chemistry, Pharmacology and Toxicology of a Benzodifuran Derivative Producing LSD-Like Effects
Bromo-DragonFly is a potent and long-acting psychedelic drug producing both LSD-like effects and amphetamine activation. This drug appeared within the recreational drug market in the early 2000s,… Expand