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The free‐exploratory paradigm: an effective method for measuring neophobic behaviour in mice and testing potential neophobia‐reducing drugs
Results demonstrate that drugs which bind in a non-selective manner to heterogeneous benzodiazepine recognition sites were very effective in reducing neophobia in BALB/c mice, whereas 5-HT-interacting drugs were unable to counteract their neophobic behaviour.
The defense system of fear: behavior and neurocircuitry
  • R. Misslin
  • Psychology, Medicine
    Neurophysiologie Clinique/Clinical…
  • 1 April 2003
Acute and chronic treatment with 5-HT reuptake inhibitors differentially modulate emotional responses in anxiety models in rodents
The increased availability of 5-HT resulting here from reuptake inhibition seems to initially result in an increased emotional reactivity which, however, subsequently disappears during chronic treatment.
5-HT1B receptor knock out — behavioral consequences
Influence of dystrophin-gene mutation onmdx mouse behavior. I. Retention deficits at long delays in spontaneous alternation and bar-pressing tasks
Retention impairments at long delays in mutantmdx mice suggest a role of dystrophin in long-term consolidation processes.
m-Chlorophenylpiperazine enhances neophobic and anxious behaviour in mice.
Results suggest that mCPP enhances emotional responses towards novel and aversive places and increased activity of serotonin may play a role in regulating certain forms of emotional behaviour in animals.