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Higher isoprenoids—VIII: Diterpenoids from the oleoresin of hardwickia pinnata part 1: hardwickiic acid
Abstract The oleoresin from Hardwickia pinnata Roxb. is shown to be a complex blend of sesquiterpenes and diterpenes. (−)-Copaene, (−)-caryophyllene and humulene account for over 90% of theExpand
Modern drug development from traditional medicinal plants using radioligand receptor‐binding assays
  • R. Misra
  • Medicine
  • Medicinal research reviews
  • 1 November 1998
The total crude extracts of many of these plants showed potent selectivity to various receptors, especially γ‐Amino Butyric Acid (GABAA), N‐Methyl‐D‐Aspartic Acid (NMDA), and MAO receptors, which are presumed to be involved in mental disorders. Expand
On the conditions for C-6 epimerization of the penicillin nucleus by a β-elimination mechanism
The effects of temperature, the substitution pattern at C-5 and C-6, and the base are employed to delineate the conditions for proton abstraction from C-6 of the penicillin nucleus by carbanion orExpand
Structure of fredericamycin A, an antitumor antibiotic of a novel skeletal type; spectroscopic and mass spectral characterization.
The novel spiro ring antibiotic exhibits unusual 1H and 13C NMR spectroscopic and chemical behavior, not previously observed in other antibiotic structures. Expand