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Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement
TLDR
GBHs are the most heavily applied herbicide in the world and usage continues to rise; Worldwide, GBHs often contaminate drinking water sources, precipitation, and air, especially in agricultural regions and regulatory estimates of tolerable daily intakes for glyphosate in the United States and European Union are based on outdated science. Expand
Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize.
TLDR
Results can be explained by the non linear endocrine-disrupting effects of Roundup, but also by the overexpression of the transgene in the GMO and its metabolic consequences. Expand
Major Pesticides Are More Toxic to Human Cells Than Their Declared Active Principles
TLDR
8 formulations out of 9 pesticides tested were up to one thousand times more toxic than their active principles, challenging the relevance of the acceptable daily intake for pesticides because this norm is calculated from the toxicity of the active principle alone. Expand
Potential toxic effects of glyphosate and its commercial formulations below regulatory limits.
TLDR
A coherent body of evidence is revealed indicating that GlyBH could be toxic below the regulatory lowest observed adverse effect level for chronic toxic effects, which includes teratogenic, tumorigenic and hepatorenal effects. Expand
Ethoxylated adjuvants of glyphosate-based herbicides are active principles of human cell toxicity.
TLDR
It is demonstrated that all formulations are more toxic than glyphosate, and it is demonstrated in addition that POE-15 induces necrosis when its first micellization process occurs, by contrast to glyphosate which is known to promote endocrine disrupting effects after entering cells. Expand
Glyphosate Exposure in a Farmer’s Family
TLDR
A more detailed following of agricultural practices and family exposures should be advocated together with information and recommendations, as oral or dermal absorptions could explain the differential pesticide excretions, even in family members at a distance from the fields. Expand
Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide.
TLDR
The conclusions of long-term NK603 and Roundup toxicities came from the statistically highly discriminant findings at the biochemical level in treated groups in comparison to controls, because these findings do correspond in an blinded analysis to the pathologies observed in organs, that were in turn linked to the deaths by anatomopathologists. Expand
Transcriptome profile analysis reflects rat liver and kidney damage following chronic ultra-low dose Roundup exposure
TLDR
It is suggested that chronic exposure to a GBH in an established laboratory animal toxicity model system at an ultra-low, environmental dose can result in liver and kidney damage with potential significant health implications for animal and human populations. Expand
Cytotoxicity on human cells of Cry1Ab and Cry1Ac Bt insecticidal toxins alone or with a glyphosate‐based herbicide
TLDR
It is argued that modified Bt toxins are not inert on nontarget human cells, and that they can present combined side‐effects with other residues of pesticides specific to GM plants. Expand
Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide
The impairment of liver function by low environmentally relevant doses of glyphosate-based herbicides (GBH) is still a debatable and unresolved matter. Previously we have shown that rats administeredExpand
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