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Sigma receptors: biology and function.
Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism
Characterization of two novel sigma receptor ligands: antidystonic effects in rats suggest sigma receptor antagonism.
- R. Matsumoto, W. Bowen, M. A. Tom, V. N. Vo, D. Truong, B. de Costa
- BiologyEuropean journal of pharmacology
BD1047 and BD1063 appear to act as antagonists at sigma sites and may represent promising new tools for probing other functional effects associated with sigma binding sites.
Sigma receptors: potential medications development target for anti-cocaine agents.
Involvement of sigma (σ) receptors in the acute actions of methamphetamine: Receptor binding and behavioral studies
Pharmacology of dextromethorphan: Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use.
Attenuation of methamphetamine-induced effects through the antagonism of sigma (σ) receptors: Evidence from in vivo and in vitro studies
Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan
- Linda Nguyen, M. Robson, J. Healy, Anna Scandinaro, R. Matsumoto
- Biology, PsychologyPloS one
- 28 February 2014
Data suggest that dextromethorphan exerts some of its antidepressant actions through σ1 receptors, which has been hypothesized to display rapid-acting antidepressant activity based on pharmacodynamic similarities to the N-methyl-D-aspartate receptor antagonist ketamine.
GABA receptors: are cellular differences reflected in function?
- R. Matsumoto
- BiologyBrain Research Reviews
- 1 July 1989