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The horseradish peroxidase-catalyzed oxidation of 3,5,3',5'-tetramethylbenzidine. Free radical and charge-transfer complex intermediates.
NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.
The hypothesis that free radicals from NADPH oxidase in hepatic Kupffer cells play a predominant role in the pathogenesis of early alcohol-induced hepatitis by activating NF-kappaB, which activates production of cytotoxic TNF-alpha is strongly supported.
Mitochondrial Dysfunction in SOD1G93A-Bearing Astrocytes Promotes Motor Neuron Degeneration: Prevention by Mitochondrial-Targeted Antioxidants
Evidence that mitochondrial dysfunction in astrocytes critically influences motor neuron survival is provided and the potential pharmacological utility of mitochondrial-targeted antioxidants in ALS treatment is supported.
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?
Evidence for free radical formation during the oxidation of 2'-7'-dichlorofluorescin to the fluorescent dye 2'-7'-dichlorofluorescein by horseradish peroxidase: possible implications for oxidative…
Redox cycling and sulphydryl arylation; their relative importance in the mechanism of quinone cytotoxicity to isolated hepatocytes.
Phenoxyl Free Radical Formation during the Oxidation of the Fluorescent Dye 2′,7′-Dichlorofluorescein by Horseradish Peroxidase
It is demonstrated that DCFH cannot be used conclusively to measure superoxide or hydrogen peroxide formation in cells undergoing oxidative stress.
The role of Kupffer cell oxidant production in early ethanol-induced liver disease.
Photoreduction of the fluorescent dye 2'-7'-dichlorofluorescein: a spin trapping and direct electron spin resonance study with implications for oxidative stress measurements.
In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide: a model for ARDS
- Keizo Sato, M. Kadiiska, R. Mason
- Biology, MedicineFASEB journal : official publication of the…
- 1 November 2002
In vivo lipid‐derived free radical formation by NADPH oxidase in acute lung injury induced by lipopolysaccharide is investigated, using rats treated with intratracheal instillation of LPS as a model for ARDS.