• Publications
  • Influence
Platelet-rich plasma: Growth factor enhancement for bone grafts.
TLDR
Monoclonal antibody assessment of cancellous cellular marrow grafts demonstrated cells that were capable of responding to the growth factors by bearing cell membrane receptors and evidenced a radiographic maturation rate 1.62 to 2.16 times that of grafts without platelet-rich plasma. Expand
Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment.
TLDR
Pre-therapy dental care reduces this incidence, and non-surgical dental procedures can prevent new cases, and effective control to a pain free state without resolution of the exposed bone is 90.1% effective using a regimen of antibiotics along with 0.12% chlorohexidine antiseptic mouth. Expand
American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaws--2009 update.
TLDR
This update contains revisions to the diagnosis and staging and management strategies and highlights the status of basic science research. Expand
American Association of Oral and Maxillofacial Surgeons position paper on bisphosphonate-related osteonecrosis of the jaw - 2009 update.
TLDR
The knowledge base and experience in ddressing BRONJ has expanded, necessitating modfications and refinements to the original Position Paper. Expand
Osteoradionecrosis: a new concept of its pathophysiology.
  • R. Marx
  • Medicine
  • Journal of oral and maxillofacial surgery…
  • 1 May 1983
TLDR
The classic sequence in the pathogenesis of osteoradionecrosis of the jaws has been accepted as radiation, trauma, and infection, but a new one more accurately describing the biochemical and cellular pathology is offered. Expand
A new concept in the treatment of osteoradionecrosis.
  • R. Marx
  • Medicine
  • Journal of oral and maxillofacial surgery…
  • 1 June 1983
TLDR
Hyperbaric oxygen and aggressive surgery in a progressively staged manner were used to achieve complete resolution of osteoradionecrosis of the mandible in 58 patients, and function was restored in all patients. Expand
Practical guidelines for the prevention, diagnosis, and treatment of osteonecrosis of the jaw in patients with cancer.
TLDR
An increased awareness of the potential risk of ONJ in patients receiving bisphosphonate therapy is needed and close coordination between the treating physician and oral surgeon and/or a dental specialist is strongly recommended in making treatment decisions. Expand
De novo bone induction by recombinant human bone morphogenetic protein-2 (rhBMP-2) in maxillary sinus floor augmentation.
TLDR
This first randomized controlled trial demonstrating de novo organ tissue growth in humans from a recombinant human protein safely induced adequate bone for the placement and functional loading of endosseous dental implants in patients requiring staged maxillary sinus floor augmentation. Expand
Studies in the radiobiology of osteoradionecrosis and their clinical significance
TLDR
Clinical guidelines for the management of irradiated patients with osteoradionecrosis include a recommendation for deferring radiation treatment for 21 days after tissue wounding, if possible; a relative contraindication to wounding tissue during a radiation course; a recommend for the use of hyperbaric oxygen before wounding; and a strong recommendation to provide comprehensive dental care to the irradiated patient. Expand
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