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Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression
TLDR
It is found that subjects with a comorbid depressive syndrome had greater awareness of their mental illness, its social consequences and treatment efficacy, but poorer overall QOL, especially in the physical, psychological health, social relationships and environmental domains. Expand
Screening for depression among acutely ill geriatric inpatients with a short Geriatric Depression Scale.
TLDR
Both shorter versions of the GDS may be utilized in screening for depression among acutely ill geriatric inpatients. Expand
Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders
TLDR
The frequency of the common C667 T variant of the enzyme methylenetetrahydrofolate reductase in controls and patients of Chinese descent provided some evidence of increased risk for individuals with the T-containing genotypes. Expand
Tardive Dyskinesia Among Chinese and Malay Patients With Schizophrenia
TLDR
It is concluded that suggested differences in interethnic rates of TD among Chinese, Malays, and Westerners are unlikely to exist and that any variation in prevalence is more likely to be determined by differences in duration of exposure and dose levels of neuroleptic drugs. Expand
Psychosocial interventions with art, music, Tai Chi and mindfulness for subsyndromal depression and anxiety in older adults: A naturalistic study in Singapore
TLDR
A community‐based psychosocial intervention program is evaluated and its effect on mental health outcomes in Singaporean older adults is evaluated. Expand
Tumor necrosis factor-alpha gene promoter polymorphisms in chronic schizophrenia.
TLDR
The -308 polymorphism or another genetic variant in linkage disequilibrium with it could be a susceptibility factor for chronic schizophrenia. Expand
Risperidone in the treatment of first episode psychosis.
TLDR
Overall the therapy of first-episode psychosis patients with risperidone was effective and safe and the CGI scores of all patients improved at endpoint. Expand
Physical comorbidity, insight, quality of life and global functioning in first episode schizophrenia: A 24-month, longitudinal outcome study
TLDR
FES patients with physical comorbidity had greater awareness into the consequences of their psychiatric illness at 12 months, the need for treatment at 12 and 18 months, and better improvement of PANSS total and general psychopathology subscale scores at 24 months, indicating better subjective rating of quality of life and objective measure of their global functioning prospectively. Expand
An inter-ethnic comparison study of clozapine dosage, clinical response and plasma levels
TLDR
Compared to Caucasian patients, Asian patients appeared to have a lower dosage requirement for clinical efficacy, and appropriate dose adjustment should be considered in Asian patients receiving maintenance clozapine therapy in clinical practice. Expand
The effects of paroxetine, alone and in combination with alcohol on psychomotor performance and cognitive function in the elderly
TLDR
The pattern of results indicated that paroxetine had little or no effect on most of the test variables, and in some instances improved information processing ability, in marked contrast to the lorazepam verum which produced sedation and disruption of performance. Expand
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