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Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology.
Coronary heart disease (CHD) is the leading cause of death and disability worldwide. Despite current therapy, the morbidity and mortality for patients with CHD remains significant. The most important… Expand
Nutritional mechanisms that influence cardiovascular disease.
- R. De Caterina, A. Zampolli, S. Del Turco, R. Madonna, M. Massaro
- The American journal of clinical nutrition
- 1 February 2006
Current evidence suggests that most significant risk factors for heart disease have been identified. Although age, sex, and genetics are important unmodifiable risk factors, most new cases of acute… Expand
Novel targets and future strategies for acute cardioprotection: Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart
Ischaemic heart disease and the heart failure that often results, remain the leading causes of death and disability in Europe and worldwide. As such, in order to prevent heart failure and improve… Expand
Cellular and molecular mechanisms of vascular injury in diabetes--part I: pathways of vascular disease in diabetes.
Diabetes-induced micro- and macrovascular complications are the major causes of morbidity and mortality in diabetic patients. While hyperglycemia is a key factor for the pathogenesis of diabetic… Expand
Left Ventricular Assist Devices and Gastrointestinal Bleeding: A Narrative Review of Case Reports and Case Series
The use of left ventricular assist devices (LVADs) has become a state‐of‐the‐art therapy for advanced cardiac heart failure; however, multiple reports in the literature describe an increased risk for… Expand
Transplantation of adipose tissue mesenchymal cells conjugated with VEGF-releasing microcarriers promotes repair in murine myocardial infarction.
RATIONALE Engraftment and survival of transplanted stem or stromal cells in the microenvironment of host tissues may be improved by combining such cells with scaffolds to delay apoptosis and enhance… Expand
Insulin enhances vascular cell adhesion molecule-1 expression in human cultured endothelial cells through a pro-atherogenic pathway mediated by p38 mitogen-activated protein-kinase
- R. Madonna, A. Pandolfi, M. Massaro, A. Consoli, R. D. Caterina
- Biology, Medicine
- 1 March 2004
Aims/hypothesisAlthough hyperinsulinaemia in Type 2 diabetes in states of insulin resistance is a risk factor for atherosclerotic vascular disease, underlying mechanisms are poorly understood. We… Expand
n-3 Fatty Acids in the Treatment of Diabetic Patients
The current interest for the use of n-3 (polyunsaturated) fatty acids in vascular disease can be originally tracked to observations in Greenland Inuits (Eskimos), revealing a lower prevalence of… Expand
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology
Abstract Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting considerable interest in the cardiovascular field as the wide range of their functions is… Expand
Cellular and molecular mechanisms of vascular injury in diabetes--part II: cellular mechanisms and therapeutic targets.
Although the mechanisms by which insulin-resistance and hyperglycemia lead to cardiovascular disease are still incompletely understood, all mechanisms apparently converge on the vessel wall and the… Expand