R. MacKay

Publications155
h-index35
Citations3,435
Highly Influential Citations173
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Multiple DNA markers differentiate Sarcocystis neurona and Sarcocystis falcatula.
Studies designed to investigate the causative agent of equine protozoal myeloencephalitis and its life cycle have been hampered by the marked similarity of Sarcocystis neurona to other Sarcocystis… Expand
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Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate.
Work in humans and laboratory animals has identified a central role for cytokines and chemokines in development and persistence of lower airway inflammation. The objectives of this study were to… Expand
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Virulent and avirulent strains of equine arteritis virus induce different quantities of TNF-alpha and other proinflammatory cytokines in alveolar and blood-derived equine macrophages.
Equine arteritis virus (EAV) infects endothelial cells (ECs) and macrophages in horses, and many of the clinical manifestations of equine viral arteritis (EVA) reflect vascular injury. To further… Expand
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The nine-banded armadillo (Dasypus novemcinctus) is an intermediate host for Sarcocystis neurona.
The nine-banded armadillo (Dasypus novemcinctus) is an intermediate host of at least three species of Sarcocystis, Sarcocystis dasypi, Sarcocystis diminuta, and an unidentified species; however, life… Expand
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The striped skunk (Mephitis mephitis) is an intermediate host for Sarcocystis neurona.
Striped skunks, initially negative for antibodies to Sarcocystis neurona, formed sarcocysts in skeletal muscles after inoculation with S. neurona sporocysts collected from a naturally infected… Expand
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Are Sarcocystis neurona and Sarcocystis falcatula synonymous? A horse infection challenge.
Equine protozoal myeloencephalitis (EPM) is a debilitating neurologic disease of the horse. The causative agent. Sarcocystis neurona, has been suggested to be synonymous with Sarcocystis falcatula,… Expand
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Viability of Sarcocystis neurona sporocysts and dose titration in gamma-interferon knockout mice.
Gamma-interferon knockout mice have become the model animal used for studies on Sarcocystis neurona. In order to determine the viability of S. neurona sporocysts and to evaluate the course of the… Expand
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Effects of polymyxin B and Salmonella typhimurium antiserum on horses given endotoxin intravenously.
Polymyxin B and an antiserum against an Re mutant Salmonella typhimurium were evaluated for protective effect in an equine model endotoxemia. Six 3- to 5-month-old foals were given endotoxin (0.25… Expand
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Risk factors associated with fecal Salmonella shedding among hospitalized horses with signs of gastrointestinal tract disease.
OBJECTIVE To estimate prevalence of and identify risk factors for fecal Salmonella shedding among hospitalized horses with signs of gastrointestinal tract disease. DESIGN Cross-sectional study. … Expand
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Naturally occurring Sarcocystis infection in domestic cats (Felis catus).
Equine protozoal myeloencephalitis is an important neurological disease of horses in the United States. Consequently, there is an active research effort to identify hosts associated with the primary… Expand
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