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Oxidative stress in the hippocampus after pilocarpine‐induced status epilepticus in Wistar rats
TLDR
It is suggested that GSH and catalase activity play an antioxidant role in the hippocampus during status epilepticus, due to a decrease in GSH concentration and an increase in lipid peroxidation and nitrite content. Expand
Effects of Levetiracetam in Lipid Peroxidation Level, Nitrite–Nitrate Formation and Antioxidant Enzymatic Activity in Mice Brain After Pilocarpine-Induced Seizures
TLDR
The present data suggest that the protective effects of LEV against pilocarpine-induced seizures can be mediated, at least in part, by reduction of lipid peroxidation and hippocampal oxidative stress. Expand
Phytol, a diterpene alcohol, inhibits the inflammatory response by reducing cytokine production and oxidative stress
TLDR
The results suggest that phytol attenuates the inflammatory response by inhibiting neutrophil migration that is partly caused by reduction in IL‐1β and TNF‐α levels and oxidative stress. Expand
The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures
TLDR
The hypothesis that oxidative stress in hippocampus occurs during seizures induced by pilocarpine is supported, proving that brain damage induced by the oxidative process plays a crucial role in seizures pathogenic consequences, and imply that strong protective effect could be achieved using lipoic acid as an antioxidant. Expand
Neuroprotective actions of vitamin C related to decreased lipid peroxidation and increased catalase activity in adult rats after pilocarpine-induced seizures
TLDR
The results can suggest that neuroprotective effects of vitamin C in adult rats can be the result of reduced lipid peroxidation levels and increase of catalase activity after seizures and status epilepticus induced by pilocarpine. Expand
Antioxidant Effects of Nerolidol in Mice Hippocampus After Open Field Test
TLDR
The hypothesis that oxidative stress occurs in hippocampus is supported and nerolidol showed sedative effects in animals subjected to the open field test, which implies that antioxidant effects could be achieved using this sesquiterpene. Expand
Effects of lipoic acid on oxidative stress in rat striatum after pilocarpine-induced seizures
TLDR
The hypothesis that oxidative stress in striatum occurs during seizures induced by pilocarpine is supported, proving that brain damage induced by the oxidative process plays a crucial role in seizures pathogenic consequences, and imply that strong protective effect could be achieved using LA. Expand
Evaluation of acute toxicity of a natural compound (+)-limonene epoxide and its anxiolytic-like action
TLDR
It is suggested that acute administration of the (+)-limonene epoxide exerts an anxiolytic-like effect on mice, and it could serve as a new approach for the treatment anxiety, since it practically does not produce toxic effects. Expand
Anxiolytic-like effects of carvacryl acetate, a derivative of carvacrol, in mice
TLDR
In conclusion, carvacryl acetate seems to have an anxiolytic-like effect, probably due to GABAergic agonist action, without psychomotor side effects. Expand
Vitamin C antioxidant effects in hippocampus of adult Wistar rats after seizures and status epilepticus induced by pilocarpine
TLDR
The results suggests that the vitamin C can exert antioxidant and anticonvulsive effects in adult rats, suggesting that this vitamin can be able by reduction of lipid peroxidation content and increased of catalase enzymatic activity which cerebral compensatory mechanisms in free radical formation during SE. Expand
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