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Multiple chromatographic fingerprinting and its application to the quality control of herbal medicines
Abstract Recently, chromatographic fingerprinting has become one of the most powerful approaches to quality control of herbal medicines. However, the performance of reported chromatographicExpand
Antiviral amentoflavone from Selaginella sinensis.
  • S. C. Ma, P. But, +4 authors R. Lin
  • Biology, Medicine
  • Biological & pharmaceutical bulletin
  • 1 March 2001
Amentoflavone showed potent antiviral activity against respiratory syncytial virus (RSV) and three other flavonoids were isolated from the ethanol extract of Selaginella sinensis. Expand
Phenolic Constituents of Selaginella doederleinii.
Lignans are described here for the first time in the family Selaginellaceae for their cytotoxic activity against L 929 murine cells accounts for the use of the plant in traditional Chinese medicine as an anticancer agent. Expand
Structure activity relationships of aristolochic acid analogues: toxicity in cultured renal epithelial cells.
BACKGROUND Aristolochia species are nephrotoxic and carcinogenic. Recent studies showed that aristolochic acid (AA) could induce acute renal failure and tubular lesions in several species andExpand
Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MS(E).
The results showed that the most important CRF-related metabolites were polyunsaturated fatty acids, indoxyl sulfate, and p-cresyl sulfates, which may be helpful to further understand the TGF-β1 mechanisms of tubulointerstitial fibrosis. Expand
Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury in rats.
It is indicated that FLP treatment can ameliorate CKD by intervening in some dominating metabolic pathways, such as adenine metabolism and amino acid metabolism. Expand
Urinary metabonomics study on biochemical changes in an experimental model of chronic renal failure by adenine based on UPLC Q-TOF/MS.
This work shows that metabonomics method is a valuable tool in CRF mechanism study and assists in clinical diagnosis of CRF. Expand
Ultra Performance Liquid Chromatography-Based Metabonomic Study of Therapeutic Effect of the Surface Layer of Poria cocos on Adenine-Induced Chronic Kidney Disease Provides New Insight into
Changes in serum metabolites indicate that the perturbations of phospholipids metabolism, energy metabolism and amino acid metabolism are related to adenine-induced CKD and to the interventions of FLP on all the three metabolic pathways. Expand
Serum metabonomics study of adenine-induced chronic renal failure in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry
It is proved that metabonomics is a promising tool for disease research by indicating the perturbations of amino acid metabolism and phospholipid metabolism in adenine-induced CRF rats. Expand
Metabolomics insights into chronic kidney disease and modulatory effect of rhubarb against tubulointerstitial fibrosis
Treatment with EA, BU and PE extracts of rhubarb improved renal function and histopathological abnormalities including interstitial fibrosis and inflammation, and either fully or partially reversed the abnormalities of the urinary metabolites. Expand