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  • Patrick S Ward, J. Patel, +13 authors C. Thompson
  • Biology, Medicine
  • Cancer cell
  • 2010 (First Publication: 16 March 2010)
  • The somatic mutations in cytosolic isocitrate dehydrogenase 1 (IDH1) observed in gliomas can lead to the production of 2-hydroxyglutarate (2HG). Here, we report that tumor 2HG is elevated in a highExpand