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Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations
TLDR
The degree to which adaptation to a uniform environment among independently evolving asexual populations is associated with increasing divergence of those populations is assessed, consistent with theoretical expectations that do not invoke divergence due to multiple fitness peaks in a Wrightian evolutionary landscape.
Genome evolution and adaptation in a long-term experiment with Escherichia coli
TLDR
Although adaptation decelerated sharply, genomic evolution was nearly constant for 20,000 generations, which is usually viewed as the signature of neutral evolution, but several lines of evidence indicate that almost all of these mutations were beneficial.
Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation
TLDR
The dynamics of evolutionary adaptation, the genetic bases of adaptation, tradeoffs and the environmental specificity of adaptation are examined, the origin and evolutionary consequences of mutators, and the process of drift decay in very small populations are examined.
The fate of competing beneficial mutations in an asexual population
TLDR
The beneficial mutation rate and the distribution of mutational effects from changes in mean fitness in an evolving E. coli population are estimated.
Long-term experimental evolution in Escherichia coli
TLDR
The degree to which adaptation to a uniform environment among independently evolving asexual populations is associated with increasing divergence of those populations is assessed, which is consistent with theoretical expectations that do not invoke divergence due to multiple fitness peaks in a Wrightian evolutionary landscape.
The Black Queen Hypothesis: Evolution of Dependencies through Adaptive Gene Loss
ABSTRACT Reductive genomic evolution, driven by genetic drift, is common in endosymbiotic bacteria. Genome reduction is less common in free-living organisms, but it has occurred in the numerically
Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations.
TLDR
The results support a Wrightian interpretation, in which chance events (mutation and drift) play an important role in adaptive evolution, as do the complex genetic interactions that underlie the structure of organisms.
The evolutionary origin of complex features
TLDR
Findings show how complex functions can originate by random mutation and natural selection.
Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population
TLDR
Sign epistasis was rare in this genome-wide study, in contrast to its prevalence in an earlier study of mutations in a single gene, which supported models in which negative epistasis contributes to declining rates of adaptation over time.
Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli
TLDR
It is suggested that historical contingency is especially important when it facilitates the evolution of key innovations that are not easily evolved by gradual, cumulative selection.
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