• Publications
  • Influence
Descending pathways in motor control.
  • R. Lemon
  • Psychology, Medicine
  • Annual review of neuroscience
  • 17 June 2008
This review explores to what extent descending pathways are highly conserved across species and concludes that there are actually rather widespread species differences, for example, in the transmission of information from the corticospinal tract to upper limb motoneurons. Expand
Corticospinal Function and Voluntary Movement
The background relationships between structure and function, and the dynamic nature of cortical organization, are described. Expand
Preconditioning of Low-Frequency Repetitive Transcranial Magnetic Stimulation with Transcranial Direct Current Stimulation: Evidence for Homeostatic Plasticity in the Human Motor Cortex
Changing the initial state of the motor cortex by a period of DC polarization reversed the conditioning effects of 1 Hz rTMS, suggesting the existence of a homeostatic mechanism in the human motor cortex that stabilizes corticospinal excitability within a physiologically useful range. Expand
Contralateral and ipsilateral EMG responses to transcranial magnetic stimulation during recovery of arm and hand function after stroke.
We examined the relationship between the recovery of hand and arm function in a group of hemiplegic stroke patients and the presence of short-latency EMG responses to transcranial magneticExpand
Relation between cerebral activity and force in the motor areas of the human brain.
1. Positron emission tomography (PET) studies were performed in six normal right-handed male volunteers (age 30 +/- 3) to investigate the relationship between cerebral activation as measured byExpand
How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain?
TDCS is an effective means of provoking sustained and widespread changes in regional neuronal activity and the extensive spatial and temporal effects of tDCS need to be taken into account when tDCS is used to modify brain function. Expand
Macaque ventral premotor cortex exerts powerful facilitation of motor cortex outputs to upper limb motoneurons.
Some motor effects evoked from F5 may be mediated by corticocortical inputs to M1 impinging on interneurons generating late corticospinal I waves, similar mechanisms may allow F5 to modulate grasp-related outputs from M1. Expand
Preconditioning with transcranial direct current stimulation sensitizes the motor cortex to rapid-rate transcranial magnetic stimulation and controls the direction of after-effects
It is shown that magnitude and direction of after-effects induced by rapid-rate rTMS depend on the state of cortical excitability before stimulation and can be tuned by preconditioning with transcranial direct current stimulation (tDCS). Expand
Can experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans?
Experiments in nonhuman primates expedite the translation of treatments for spinal cord injury in humans and show results that are similar to those in humans. Expand
State of the art: Physiology of transcranial motor cortex stimulation
An updated overview of human and animal studies on the physiologic mechanisms of intact motor cortex stimulation is presented and direct recording of the evoked corticospinal output has provided important insight into the excitatory and inhibitory phenomena produced by cerebral cortex stimulation. Expand