R. Landgraf

Publications299
h-index48
Citations8,451
Highly Influential Citations223
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Attenuated neuroendocrine responses to emotional and physical stressors in pregnant rats involve adenohypophysial changes
1 The responsiveness of the rat hypothalamo‐pituitary‐adrenal (HPA) axis and hypothalamo‐neurohypophysial system (HNS) to emotional (elevated plus‐maze) and physical (forced swimming) stressors and… Expand
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Post-prandial decrease of circulating human ghrelin levels
Ghrelin, an endogenous ligand of the GH secretagogue-receptor, has recently been shown to stimulate GH secretion and to have orexigenic and adipogenic effects in rodents, but little is known about… Expand
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Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV‐1‐infected patients
Background:The use of protease inhibitors in the treatment of HIV-1 infection is associated with the new onset of diabetes mellitus, hyperlipidaemia and lipodystrophy. It is unclear whether these… Expand
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Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study.
OBJECTIVE To examine the correlates of patient and provider attitudes toward insulin therapy. RESEARCH DESIGN AND METHODS Data are from surveys of patients with type 2 diabetes not taking insulin… Expand
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Simultaneous microdialysis in blood and brain: oxytocin and vasopressin release in response to central and peripheral osmotic stimulation and suckling in the rat.
Simultaneous microdialysis in blood and brain has been used to monitor the release of both oxytocin and vasopressin into the systemic circulation (jugular vein/right atrium) and within the… Expand
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Anxiolytic and Anti-Stress Effects of Brain Prolactin: Improved Efficacy of Antisense Targeting of the Prolactin Receptor by Molecular Modeling
We provide the first evidence that prolactin is a neuromodulator of behavioral and neuroendocrine stress coping in the rat. In virgin female and male rats, intracerebral infusion of ovine prolactin… Expand
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Release of Vasopressin within the Rat Paraventricular Nucleus in Response to Emotional Stress: A Novel Mechanism of Regulating Adrenocorticotropic Hormone Secretion?
The effects of emotional stressors on the release of arginine vasopressin (AVP) and oxytocin (OXT) within the rat hypothalamus and the origin and physiological significance of AVP released within the… Expand
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Attenuation of Hypothalamic‐Pituitary‐Adrenal Axis Stress Responses in Late Pregnancy: Changes in Feedforward and Feedback Mechanisms
The hypothalamic‐pituitary‐adrenal axis is hyporesponsive to stress in late pregnancy, exemplified as reduced adrenocorticotropic hormone (ACTH) and corticosterone responses to restraint, but the… Expand
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Blood—Brain Barrier and Peptides
The brain is both the source and the recipient of peptide signals. The question is: Do endogenous, blood-borne peptide molecules influence brain function? Brain regions with the tight capillaries of… Expand
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Septal and hippocampal release of vasopressin and oxytocin during late pregnancy and parturition in the rat.
The push-pull perfusion technique, in conjunction with specific radioimmunoassays, was used to monitor the release of both arginine vasopressin (AVP) and oxytocin (OXT) within distinct limbic brain… Expand
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