• Publications
  • Influence
A Gender Gap in Autoimmunity
There are many differences between men and women in their susceptibility to particular autoimmune diseases, the characteristics of the disease at onset, and disease severity. In a Perspective in thisExpand
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International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies
Anti-nuclear antibodies (ANA) are fundamental for the diagnosis of autoimmune diseases, and have been determined by indirect immunofluorescence assay (IIFA) for decades. As the demand for ANA testingExpand
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The American College of Rheumatology nomenclature and case definitions for neuropsychiatric lupus syndromes.
OBJECTIVE To develop a standardized nomenclature system for the neuropsychiatric syndromes of systemic lupus erythematosus (NPSLE). METHODS An international, multidisciplinary committeeExpand
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Range of antinuclear antibodies in "healthy" individuals.
OBJECTIVE To determine the range of antinuclear antibodies (ANA) in "healthy" individuals compared with that in patients with systemic lupus erythematosus (SLE), systemic sclerosis (SSc;Expand
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A role for the polymorphism at position 247 of the beta2-glycoprotein I gene in the generation of anti-beta2-glycoprotein I antibodies in the antiphospholipid syndrome.
OBJECTIVE To determine the frequencies at which either a valine or leucine occurs at position 247 in the beta2-glycoprotein I (beta2GPI) gene of normal individuals of the Caucasian, African American,Expand
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The role of sex hormones in systemic lupus erythematosus.
  • R. Lahita
  • Medicine
  • Current opinion in rheumatology
  • 1 September 1999
The disease systemic lupus erythematosus (SLE) is a complex one. One major clinical manifestation that relates to both cause and pathogenesis of all autoimmune diseases but specifically SLE is theExpand
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Fequency of antibodies to the cholesterol transport protein apolipoprotein A1 in patients with SLE
In examining reasons for premature atherosclerosis in systemic lupus erythematosus (SLE), we previously reported low levels of the cholesterol transport protein apolipoprotein A1 (apoA1) in theseExpand
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Alterations of estrogen metabolism in systemic lupus erythematosus.
Estradiol metabolism in 10 patients with systemic lupus erythematosus (SLE) and 29 normal controls was studied by measurement of urinary metabolites after injection of labeled 3H-estradiol. PatientsExpand
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Low plasma androgens in women with systemic lupus erythematosus.
The high ratio of women with systemic lupus erythematosus (SLE) has remained unexplained, despite the recent description of metabolic abnormalities of estrogen and androgen metabolism. Alterations ofExpand
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Pragmatic approaches to therapy for systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with substantial clinical heterogeneity. Current treatments for SLE are effective at reducing morbidity and mortality but fail toExpand
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