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Mibefradil block of cloned T-type calcium channels.
- R. L. Martin, J. H. Lee, L. Cribbs, E. Perez-Reyes, D. Hanck
- BiologyJournal of Pharmacology and Experimental…
- 1 October 2000
The data are consistent with the idea that mibefradil competes for its binding site on the channel with the permeant species and that Ba(2+) is a more effective competitor than Ca(2+).
Simultaneous measurement of pH and membrane potential in rat dorsal vagal motoneurons during normoxia and hypoxia: a comparison in bicarbonate and HEPES buffers.
Arguments are presented in favor of the concept that modulation of ion channels by either pHi or pHe, or both, is responsible for the observed correlations.
The constitutive and stress inducible forms of hsp 70 exhibit functional similarities and interact with one another in an ATP- dependent fashion
- C. Brown, R. L. Martin, W. Hansen, R. Beckmann, W. Welch
- BiologyThe Journal of cell biology
- 1 March 1993
It is shown that the constitutively expressed, pre-existing hsp 73 rapidly forms a stable complex with the newly synthesized stress inducible hsp 72, and both proteins exhibit a coincident locale within the cell.
Matrix metalloproteinase inhibition limits arterial enlargements in a rodent arteriovenous fistula model.
ATP sulfurylase from trophosome tissue of Riftia pachyptila (hydrothermal vent tube worm).
A pharmacological and biochemical investigation of the venom from the platypus (Ornithorhynchus anatinus).
A C-type natriuretic peptide from the venom of the platypus (Ornithorhynchus anatinus): structure and pharmacology.
Myotoxicity studies of injectable biodegradable in-situ forming drug delivery systems.
Identification of a di-leucine motif within the C terminus domain of the Menkes disease protein that mediates endocytosis from the plasma membrane.
- M. Francis, E. E. Jones, E. Levy, R. L. Martin, S. Ponnambalam, A. Monaco
- BiologyJournal of cell science
- 1 June 1999
A di-leucine motif (L1487L1488) was essential for rapid internalisation of chimeric CD8 proteins and the full-length Menkes cDNA from the plasma membrane, and it is suggested that this motif mediates the retrieval of MNK from the Plasma membrane into the endocytic pathway, via the recycling endosomes, but is not sufficient to return the protein to the Golgi apparatus.
Reduction by general anaesthetics of group Ia excitatory postsynaptic potentials and currents in the cat spinal cord.
The results are interpreted as indicating a presynaptic site of action of both anaesthetics at the concentrations studied: the probability of release of neurotransmitter is reduced, without any detectable change in the mean duration of the postsynaptic conductance increase.