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The importance of the rat hippocampus for learning the structure of visual arrays
- D. Sanderson, J. Pearce, R. Kyd, J. Aggleton
- Psychology, Medicine
- The European journal of neuroscience
- 1 September 2006
While the rat hippocampus need not be required for all configural learning, it is important for the special case when the spatial arrangements of the elements are critical, and may be a prerequisite for the creation of mental snapshots, which underlie episodic memory. Expand
When is the perirhinal cortex necessary for the performance of spatial memory tasks?
- J. Aggleton, R. Kyd, D. Bilkey
- Medicine, Psychology
- Neuroscience & Biobehavioral Reviews
- 1 October 2004
It is argued that parallel cortical routes provide key, sensory data to the hippocampus such that in the absence of the perirhinal cortex alternative information is available and the deficits associated with perIRhinal damage may reflect difficulties that arise when task performance requires the use of ambiguous distal cues. Expand
Hippocampal place cells show increased sensitivity to changes in the local environment following prefrontal cortex lesions.
Examining how prefrontal cortex lesions affected the firing of hippocampal place cells in freely moving rats suggested that place cell firing was overly influenced by local cues in the prefrontal-lesioned animals, consistent with the hypothesis that lesions of the cortex result in a disinhibition of posterior cortex. Expand
Multiple hypothalamic sites control the frequency of hippocampal theta rhythm
Overall, it appears that at, any one time, theta frequency may be determined by a complex interplay between distinct but interacting modulatory regions in the medial hypothalamus. Expand
Complexin 1 knockout mice exhibit marked deficits in social behaviours but appear to be cognitively normal.
Together the results show that Cplx1(-/-) mice have pronounced deficits in social behaviours, which contribute to the psycho-social aspects of human diseases in which this protein is dysregulated. Expand
The effects of hippocampal system lesions on a novel temporal discrimination task for rats
- R. Kyd, J. Pearce, M. Haselgrove, E. Amin, J. Aggleton
- Medicine, Psychology
- Behavioural Brain Research
- 11 February 2008
The results not only reveal that neither the fornix nor the hippocampus is necessary for distinguishing temporal intervals within the ranges tested but also showed how under some circumstances these lesions can leave trace conditioning intact. Expand
Prefrontal cortex lesions modify the spatial properties of hippocampal place cells.
Findings indicate that prefrontal cortex normally modulates spatial responses in the hippocampus, a region implicated in memory processing. Expand
PROSTHESIS-RELATED QUALITY OF LIFE FOLLOWING THROUGH KNEE AMPUTATION – THE WAIKATO EXPERIENCE
The majority of patients fitted with a through knee prosthesis had good functional and psychosocial outcomes and when a below knee amputation is not possible, amputation at the level of the knee joint offers a satisfactory quality of life. Expand
EXETER IMPACTION GRAFTING (EIG) FOR FEMORAL AND ACETABULAR REVISION ARTHROPLASTY: A SINGLE SURGEON’S EXPERIENCE (1995–2001)
EIG is one solution for complicated revision in the presence of proximal femoral bone stock loss as well as aseptic loosening of either or both of the acetabular or femoral components. Expand
Bone and joint complications of maintenance haemodialysis and renal transplantation.
- R. Kyd
- The New Zealand medical journal
Bone and joint complications of haemodialysis and renal transplant managed at Auckland Hospital have been reviewed and total hip replacement gave good results in all cases (10 hips) without significant operative complications. Expand